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Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format Example of Fluids and Barriers of the CNS format
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open access Open Access

Fluids and Barriers of the CNS — Template for authors

Publisher: Springer
Categories Rank Trend in last 3 yrs
Developmental Neuroscience #6 of 35 up up by 1 rank
Neurology #29 of 156 -
Cellular and Molecular Neuroscience #30 of 88 down down by 9 ranks
journal-quality-icon Journal quality:
High
calendar-icon Last 4 years overview: 173 Published Papers | 1171 Citations
indexed-in-icon Indexed in: Scopus
last-updated-icon Last updated: 12/06/2020
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Related Journals

open access Open Access

Springer

Quality:  
High
CiteRatio: 6.0
SJR: 1.239
SNIP: 1.096
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CiteRatio: 9.9
SJR: 1.569
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Quality:  
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CiteRatio: 8.0
SJR: 1.779
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Journal Performance & Insights

CiteRatio

SCImago Journal Rank (SJR)

Source Normalized Impact per Paper (SNIP)

A measure of average citations received per peer-reviewed paper published in the journal.

Measures weighted citations received by the journal. Citation weighting depends on the categories and prestige of the citing journal.

Measures actual citations received relative to citations expected for the journal's category.

6.8

13% from 2019

CiteRatio for Fluids and Barriers of the CNS from 2016 - 2020
Year Value
2020 6.8
2019 6.0
2018 5.9
2017 7.1
2016 9.4
graph view Graph view
table view Table view

1.582

9% from 2019

SJR for Fluids and Barriers of the CNS from 2016 - 2020
Year Value
2020 1.582
2019 1.448
2018 1.394
2017 2.054
2016 2.005
graph view Graph view
table view Table view

1.194

1% from 2019

SNIP for Fluids and Barriers of the CNS from 2016 - 2020
Year Value
2020 1.194
2019 1.18
2018 1.208
2017 1.361
2016 1.415
graph view Graph view
table view Table view

insights Insights

  • CiteRatio of this journal has increased by 13% in last years.
  • This journal’s CiteRatio is in the top 10 percentile category.

insights Insights

  • SJR of this journal has increased by 9% in last years.
  • This journal’s SJR is in the top 10 percentile category.

insights Insights

  • SNIP of this journal has increased by 1% in last years.
  • This journal’s SNIP is in the top 10 percentile category.

Fluids and Barriers of the CNS

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Fluids and Barriers of the CNS

Approved by publishing and review experts on SciSpace, this template is built as per for Fluids and Barriers of the CNS formatting guidelines as mentioned in Springer author instructions. The current version was created on and has been used by 571 authors to write and format their manuscripts to this journal.

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Last updated on
12 Jun 2020
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ISSN
1606-8610
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Open Access
Yes
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Sherpa RoMEO Archiving Policy
White faq
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Plagiarism Check
Available via Turnitin
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Endnote Style
Download Available
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Citation Type
Numbered
[25]
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Bibliography Example
Blonder, G.E., Tinkham, M., Klapwijk, T.M.: Transition from metallic to tunneling regimes in superconducting microconstrictions: Excess current, charge imbalance, and supercurrent conversion. Phys. Rev. B 25(7), 4515–4532 (1982)

Top papers written in this journal

open accessOpen access Journal Article DOI: 10.1186/2045-8118-11-10
A new look at cerebrospinal fluid circulation
Thomas Brinker1, Edward G. Stopa1, John F Morrison1, Petra M. Klinge1

Abstract:

According to the traditional understanding of cerebrospinal fluid (CSF) physiology, the majority of CSF is produced by the choroid plexus, circulates through the ventricles, the cisterns, and the subarachnoid space to be absorbed into the blood by the arachnoid villi. This review surveys key developments leading to the tradit... According to the traditional understanding of cerebrospinal fluid (CSF) physiology, the majority of CSF is produced by the choroid plexus, circulates through the ventricles, the cisterns, and the subarachnoid space to be absorbed into the blood by the arachnoid villi. This review surveys key developments leading to the traditional concept. Challenging this concept are novel insights utilizing molecular and cellular biology as well as neuroimaging, which indicate that CSF physiology may be much more complex than previously believed. The CSF circulation comprises not only a directed flow of CSF, but in addition a pulsatile to and fro movement throughout the entire brain with local fluid exchange between blood, interstitial fluid, and CSF. Astrocytes, aquaporins, and other membrane transporters are key elements in brain water and CSF homeostasis. A continuous bidirectional fluid exchange at the blood brain barrier produces flow rates, which exceed the choroidal CSF production rate by far. The CSF circulation around blood vessels penetrating from the subarachnoid space into the Virchow Robin spaces provides both a drainage pathway for the clearance of waste molecules from the brain and a site for the interaction of the systemic immune system with that of the brain. Important physiological functions, for example the regeneration of the brain during sleep, may depend on CSF circulation. read more read less

Topics:

Cerebrospinal fluid circulation (64%)64% related to the paper, Cerebrospinal fluid (60%)60% related to the paper, Choroid plexus (53%)53% related to the paper, Subarachnoid space (52%)52% related to the paper, Blood–brain barrier (50%)50% related to the paper
View PDF
609 Citations
open accessOpen access Journal Article DOI: 10.1186/2045-8118-10-16
The hCMEC/D3 cell line as a model of the human blood brain barrier

Abstract:

Since the first attempts in the 1970s to isolate cerebral microvessel endothelial cells (CECs) in order to model the blood–brain barrier (BBB) in vitro, the need for a human BBB model that closely mimics the in vivo phenotype and is reproducible and easy to grow, has been widely recognized by cerebrovascular researchers in bo... Since the first attempts in the 1970s to isolate cerebral microvessel endothelial cells (CECs) in order to model the blood–brain barrier (BBB) in vitro, the need for a human BBB model that closely mimics the in vivo phenotype and is reproducible and easy to grow, has been widely recognized by cerebrovascular researchers in both academia and industry. While primary human CECs would ideally be the model of choice, the paucity of available fresh human cerebral tissue makes wide-scale studies impractical. The brain microvascular endothelial cell line hCMEC/D3 represents one such model of the human BBB that can be easily grown and is amenable to cellular and molecular studies on pathological and drug transport mechanisms with relevance to the central nervous system (CNS). Indeed, since the development of this cell line in 2005 over 100 studies on different aspects of cerebral endothelial biology and pharmacology have been published. Here we review the suitability of this cell line as a human BBB model for pathogenic and drug transport studies and we critically consider its advantages and limitations. read more read less

Topics:

Blood–brain barrier (51%)51% related to the paper
View PDF
517 Citations
open accessOpen access Journal Article DOI: 10.1186/2045-8118-11-26
Mechanisms of fluid movement into, through and out of the brain: evaluation of the evidence
Stephen B. Hladky1, Margery A. Barrand1

Abstract:

Interstitial fluid (ISF) surrounds the parenchymal cells of the brain and spinal cord while cerebrospinal fluid (CSF) fills the larger spaces within and around the CNS. Regulation of the composition and volume of these fluids is important for effective functioning of brain cells and is achieved by barriers that prevent free e... Interstitial fluid (ISF) surrounds the parenchymal cells of the brain and spinal cord while cerebrospinal fluid (CSF) fills the larger spaces within and around the CNS. Regulation of the composition and volume of these fluids is important for effective functioning of brain cells and is achieved by barriers that prevent free exchange between CNS and blood and by mechanisms that secrete fluid of controlled composition into the brain and distribute and reabsorb it. Structures associated with this regular fluid turnover include the choroid plexuses, brain capillaries comprising the blood-brain barrier, arachnoid villi and perineural spaces penetrating the cribriform plate. ISF flow, estimated from rates of removal of markers from the brain, has been thought to reflect rates of fluid secretion across the blood-brain barrier, although this has been questioned because measurements were made under barbiturate anaesthesia possibly affecting secretion and flow and because CSF influx to the parenchyma via perivascular routes may deliver fluid independently of blood-brain barrier secretion. Fluid secretion at the blood-brain barrier is provided by specific transporters that generate solute fluxes so creating osmotic gradients that force water to follow. Any flow due to hydrostatic pressures driving water across the barrier soon ceases unless accompanied by solute transport because water movements modify solute concentrations. CSF is thought to be derived primarily from secretion by the choroid plexuses. Flow rates measured using phase contrast magnetic resonance imaging reveal CSF movements to be more rapid and variable than previously supposed, even implying that under some circumstances net flow through the cerebral aqueduct may be reversed with net flow into the third and lateral ventricles. Such reversed flow requires there to be alternative sites for both generation and removal of CSF. Fluorescent tracer analysis has shown that fluid flow can occur from CSF into parenchyma along periarterial spaces. Whether this represents net fluid flow and whether there is subsequent flow through the interstitium and net flow out of the cortex via perivenous routes, described as glymphatic circulation, remains to be established. Modern techniques have revealed complex fluid movements within the brain. This review provides a critical evaluation of the data. read more read less

Topics:

Glymphatic system (60%)60% related to the paper, Interstitial fluid (57%)57% related to the paper, Cerebrospinal fluid (57%)57% related to the paper, Blood–brain barrier (52%)52% related to the paper, Choroid plexus (51%)51% related to the paper
View PDF
463 Citations
open accessOpen access Journal Article DOI: 10.1186/2045-8118-9-23
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation

Abstract:

The Blood–brain barrier (BBB), present at the level of the endothelium of cerebral blood vessels, selectively restricts the blood-to-brain paracellular diffusion of compounds; it is mandatory for cerebral homeostasis and proper neuronal function. The barrier properties of these specialized endothelial cells notably depend on ... The Blood–brain barrier (BBB), present at the level of the endothelium of cerebral blood vessels, selectively restricts the blood-to-brain paracellular diffusion of compounds; it is mandatory for cerebral homeostasis and proper neuronal function. The barrier properties of these specialized endothelial cells notably depend on tight junctions (TJs) between adjacent cells: TJs are dynamic structures consisting of a number of transmembrane and membrane-associated cytoplasmic proteins, which are assembled in a multimolecular complex and acting as a platform for intracellular signaling. Although the structural composition of these complexes has been well described in the recent years, our knowledge about their functional regulation still remains fragmentary. Importantly, pericytes, embedded in the vascular basement membrane, and perivascular microglial cells, astrocytes and neurons contribute to the regulation of endothelial TJs and BBB function, altogether constituting the so-called neurovascular unit. The present review summarizes our current understanding of the structure and functional regulation of endothelial TJs at the BBB. Accumulating evidence points to a correlation between BBB dysfunction, alteration of TJ complexes and progression of a variety of CNS diseases, such as stroke, multiple sclerosis and brain tumors, as well as neurodegenerative diseases like Parkinson’s and Alzheimer’s diseases. Understanding how TJ integrity is controlled may thus help improve drug delivery across the BBB and the design of therapeutic strategies for neurological disorders. read more read less

Topics:

Blood–brain barrier (58%)58% related to the paper, Tight junction (52%)52% related to the paper
View PDF
440 Citations
open accessOpen access Journal Article DOI: 10.1186/S12987-020-00230-3
A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity
Hossam Kadry1, Behnam Noorani1, Luca Cucullo2

Abstract:

The blood–brain barrier is playing a critical role in controlling the influx and efflux of biological substances essential for the brain’s metabolic activity as well as neuronal function. Thus, the functional and structural integrity of the BBB is pivotal to maintain the homeostasis of the brain microenvironment. The differen... The blood–brain barrier is playing a critical role in controlling the influx and efflux of biological substances essential for the brain’s metabolic activity as well as neuronal function. Thus, the functional and structural integrity of the BBB is pivotal to maintain the homeostasis of the brain microenvironment. The different cells and structures contributing to developing this barrier are summarized along with the different functions that BBB plays at the brain–blood interface. We also explained the role of shear stress in maintaining BBB integrity. Furthermore, we elaborated on the clinical aspects that correlate between BBB disruption and different neurological and pathological conditions. Finally, we discussed several biomarkers that can help to assess the BBB permeability and integrity in-vitro or in-vivo and briefly explain their advantages and disadvantages. read more read less

Topics:

Blood–brain barrier (51%)51% related to the paper
View PDF
384 Citations
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Frequently asked questions

1. Can I write Fluids and Barriers of the CNS in LaTeX?

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To be honest, the answer is no. The impact factor is one of the many elements that determine the quality of a journal. Few of these factors include review board, rejection rates, frequency of inclusion in indexes, and Eigenfactor. You need to assess all these factors before you make your final call.

13. What is Sherpa RoMEO Archiving Policy for Fluids and Barriers of the CNS?

SHERPA/RoMEO Database

We extracted this data from Sherpa Romeo to help researchers understand the access level of this journal in accordance with the Sherpa Romeo Archiving Policy for Fluids and Barriers of the CNS. The table below indicates the level of access a journal has as per Sherpa Romeo's archiving policy.

RoMEO Colour Archiving policy
Green Can archive pre-print and post-print or publisher's version/PDF
Blue Can archive post-print (ie final draft post-refereeing) or publisher's version/PDF
Yellow Can archive pre-print (ie pre-refereeing)
White Archiving not formally supported
FYI:
  1. Pre-prints as being the version of the paper before peer review and
  2. Post-prints as being the version of the paper after peer-review, with revisions having been made.

14. What are the most common citation types In Fluids and Barriers of the CNS?

The 5 most common citation types in order of usage for Fluids and Barriers of the CNS are:.

S. No. Citation Style Type
1. Author Year
2. Numbered
3. Numbered (Superscripted)
4. Author Year (Cited Pages)
5. Footnote

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16. Can I download Fluids and Barriers of the CNS in Endnote format?

Yes, SciSpace provides this functionality. After signing up, you would need to import your existing references from Word or Bib file to SciSpace. Then SciSpace would allow you to download your references in Fluids and Barriers of the CNS Endnote style according to Elsevier guidelines.

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