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Alan Soo Beng Khoo
Researcher at International Medical University
Publications - 22
Citations - 647
Alan Soo Beng Khoo is an academic researcher from International Medical University. The author has contributed to research in topics: Nasopharyngeal carcinoma & Nasopharyngeal neoplasm. The author has an hindex of 12, co-authored 20 publications receiving 455 citations. Previous affiliations of Alan Soo Beng Khoo include Swinburne University of Technology Sarawak Campus.
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Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review.
TL;DR: This review focuses on the antibacterial activities of curcumin against both methicillin-sensitive S. aureus (MSSA) and methiillin-resistant S.A. aUREus (MRSA), and attempts to highlight the potential challenges in the effort of developingCurcumin into a therapeutic antibacterial agent.
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Selective anticancer copper(II)-mixed ligand complexes: targeting of ROS and proteasomes
Chew Hee Ng,Siew Ming Kong,Yee Lian Tiong,Mohd Jamil Maah,Nurhazwani Sukram,Munirah Ahmad,Alan Soo Beng Khoo +6 more
TL;DR: Investigation of a series of ternary copper(II) complexes found to be effective against cervical (Hela), ovarian (SKOV3), lung, lung, NPC, lymphoma and leukemia, and colorectal cancer cell lines found the complex to be highly cytotoxic to most cancer cell types and more effective than cisplatin.
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Evaluation of extraction kits and RT-qPCR systems adapted to high-throughput platform for circulating miRNAs
TL;DR: High-throughput RT-qPCR with pre-amplification step had increased sensitivity and can be achieved with accuracy and high reproducibility through stringent experimental controls, useful for planning biomarker validation studies involving circulating miRNAs.
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Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma
Lesley Jia Wei Pua,Chun-Wai Mai,Felicia Fei-Lei Chung,Alan Soo Beng Khoo,Chee-Onn Leong,Wei-Meng Lim,Ling-Wei Hii +6 more
TL;DR: This work aims to inspire future studies further delineating JNK and p38 MAPK signaling in NPC oncogenesis which might offer important insights for better strategies in diagnosis, prognosis, and treatment decision-making in NPC patients.
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Deregulation of lipid metabolism pathway genes in nasopharyngeal carcinoma cells
TL;DR: Gene Ontology analysis of the data set revealed that EBERs upregulate the cellular lipid metabolic process and a polyphenolic flavonoid compound, quercetin, known to inhibit FASN, was found to inhibit proliferation of NPC cells.