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Ambily Ravindran Nair
Researcher at University of Hasselt
Publications - 4
Citations - 1173
Ambily Ravindran Nair is an academic researcher from University of Hasselt. The author has contributed to research in topics: Oxidative stress & Gene expression. The author has an hindex of 4, co-authored 4 publications receiving 984 citations.
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Journal ArticleDOI
Cadmium stress: an oxidative challenge
Ann Cuypers,Michelle Plusquin,Tony Remans,Marijke Jozefczak,Els Keunen,Heidi Gielen,Kelly Opdenakker,Ambily Ravindran Nair,Elke Munters,Tom Artois,Tim S. Nawrot,Jaco Vangronsveld,Kelly Smeets +12 more
TL;DR: The current review gives an overview on Cd-induced ROS production and anti-oxidative defense in organisms under different Cd regimes and the C d-induced oxidative challenge is discussed with a focus on damage and signaling as downstream responses.
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Cadmium-Induced Pathologies: Where Is the Oxidative Balance Lost (or Not)?
TL;DR: The Cd-induced oxidant/antioxidant status as well as the damage versus signalling scenario in relation to Cd toxicity are highlighted, including a section on cell proliferation and carcinogenesis.
Journal ArticleDOI
Glutathione and mitochondria determine acute defense responses and adaptive processes in cadmium-induced oxidative stress and toxicity of the kidney
Ambily Ravindran Nair,Wing-Kee Lee,Karen Smeets,Quirine Swennen,Amparo Yovanna Castro Sanchez,Frank Thévenod,Ann Cuypers +6 more
TL;DR: A clear involvement of higher mitochondria copy numbers or mass and mitochondrial function in acute defense against oxidative stress induced by Cd2+ in renal PTCs as well as in adaptive processes associated with chronic renal Cd 2+ toxicity are demonstrated.
Journal ArticleDOI
Renal cells exposed to cadmium in vitro and in vivo: normalizing gene expression data
Ambily Ravindran Nair,Karen Smeets,Els Keunen,Wing-Kee Lee,Frank Thévenod,E. Van Kerkhove,Ann Cuypers +6 more
TL;DR: This study shows that glyceraldehyde‐3‐phosphate dehydrogenase, tyrosine monooxygenase/tryptophan5‐mono Oxygenase activation‐protein, zeta polypeptide (Ywhaz) and beta‐actin (Actb) are the most stable reference genes in a kidney proximal tubular cell line exposed to moderate and high Cd concentrations.