A
André Delacourte
Researcher at French Institute of Health and Medical Research
Publications - 244
Citations - 25353
André Delacourte is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Alzheimer's disease & Tau protein. The author has an hindex of 74, co-authored 244 publications receiving 24062 citations. Previous affiliations of André Delacourte include Lille University of Science and Technology & Icahn School of Medicine at Mount Sinai.
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Journal ArticleDOI
Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS–ADRDA criteria
Bruno Dubois,Howard Feldman,Claudia Jacova,Steven T. DeKosky,Pascale Barberger-Gateau,Jeffrey L. Cummings,André Delacourte,Douglas Galasko,Serge Gauthier,Gregory A. Jicha,Kenichi Meguro,John T. O'Brien,Florence Pasquier,Philippe Robert,Martin N. Rossor,Steven Salloway,Yaakov Stern,Pieter Jelle Visser,Philip Scheltens +18 more
TL;DR: The NINCDS-ADRDA and DSM-IV-TR criteria for Alzheimer's disease (AD) are the prevailing diagnostic standards in research; however, they have now fallen behind the unprecedented growth of scientific knowledge as discussed by the authors.
Journal ArticleDOI
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders
TL;DR: Tau proteins are the major constituents of intraneuronal and glial fibrillar lesions described in Alzheimer's disease and numerous neurodegenerative disorders referred as 'tauopathies' as discussed by the authors.
Journal ArticleDOI
Revising the definition of Alzheimer's disease: a new lexicon.
Bruno Dubois,Howard Feldman,Howard Feldman,Howard Feldman,Claudia Jacova,Jeffrey L. Cummings,Steven T. DeKosky,Pascale Barberger-Gateau,André Delacourte,Giovanni B. Frisoni,Nick C. Fox,Douglas Galasko,Serge Gauthier,Harald Hampel,Gregory A. Jicha,Kenichi Meguro,John T. O'Brien,Florence Pasquier,Philippe Robert,Martin N. Rossor,Steven Salloway,Marie Sarazin,Leonardo Cruz de Souza,Yaakov Stern,Pieter Jelle Visser,Pieter Jelle Visser,Philip Scheltens +26 more
TL;DR: This paper aims to advance the scientific discussion by providing broader diagnostic coverage of the AD clinical spectrum and by proposing a common lexicon as a point of reference for the clinical and research communities.
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Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression.
Sébastien S. Hébert,Katrien Horré,Laura Nicolaï,Aikaterini S. Papadopoulou,Wim Mandemakers,Asli Silahtaroglu,Sakari Kauppinen,Sakari Kauppinen,André Delacourte,Bart De Strooper +9 more
TL;DR: It is shown here that miR-29a, -29b-1, and -9 can regulate Bace1 expression in vitro and proposed that loss of specific miRNAs can contribute to increased BACE1 and Aβ levels in sporadic AD.
Journal ArticleDOI
The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer’s disease
André Delacourte,Jean-Philippe David,Nicolas Sergeant,Luc Buée,A. Wattez,Patrick Vermersch,F. Ghozali,Catherine Fallet-Bianco,Florence Pasquier,Florence Lebert,Henri Petit,C. Di Menza +11 more
TL;DR: The relationship between NFD and Alzheimer-type dementia, and the criteria for a biochemical diagnosis of AD, are documented, and an association between AD and the extent of NFD in defined brain areas is shown.