THE DESIGN AND ANALYSIS OF EXPERIMENTS. By Oscar Kempthorne. New York, John Wiley and Sons, Inc., 1952. 631 pp. $8.50. This book by a teacher of statistics (as well as a consultant for \"experimenters\") is a comprehensive study of the philosophical background for the statistical design of experiment. It is necessary to have some facility with algebraic notation and manipulation to be able to use the volume intelligently. The problems are presented from the theoretical point of view, without such practical examples as would be helpful for those not acquainted with mathematics. The mathematical justification for the techniques is given. As a somewhat advanced treatment of the design and analysis of experiments, this volume will be interesting and helpful for many who approach statistics theoretically as well as practically. With emphasis on the \"why,\" and with description given broadly, the author relates the subject matter to the general theory of statistics and to the general problem of experimental inference. MARGARET J. ROBERTSON

The Design and Analysis of Experiments

According to W. Edwards Deming, American companies require nothing less than a transformation of management style and of governmental relations with industry. In Out of the Crisis, originally published in 1982, Deming offers a theory of management based on his famous 14 Points for Management. Management's failure to plan for the future, he claims, brings about loss of market, which brings about loss of jobs. Management must be judged not only by the quarterly dividend, but by innovative plans to stay in business, protect investment, ensure future dividends, and provide more jobs through improved product and service. In simple, direct language, he explains the principles of management transformation and how to apply them.

Out of the Crisis

Fenton chemistry encompasses reactions of hydrogen peroxide in the presence of iron to generate highly reactive species such as the hydroxyl radical and possibly others. In this review, the complex mechanisms of Fenton and Fenton-like reactions and the important factors influencing these reactions, from both a fundamental and practical perspective, in applications to water and soil treatment, are discussed. The review covers modified versions including the photoassisted Fenton reaction, use of chelated iron, electro-Fenton reactions, and Fenton reactions using heterogeneous catalysts. Sections are devoted to nonclassical pathways, by-products, kinetics and process modeling, experimental design methodology, soil and aquifer treatment, use of Fenton in combination with other advanced oxidation processes or biodegradation, economic comparison with other advanced oxidation processes, and case studies.

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Advanced Oxidation Processes for Organic Contaminant Destruction Based on the Fenton Reaction and Related Chemistry

The use of statistical techniques to build approximations of expensive computer analysis codes pervades much of today’s engineering design. These statistical approximations, or metamodels, are used to replace the actual expensive computer analyses, facilitating multidisciplinary, multiobjective optimization and concept exploration. In this paper, we review several of these techniques, including design of experiments, response surface methodology, Taguchi methods, neural networks, inductive learning and kriging. We survey their existing application in engineering design, and then address the dangers of applying traditional statistical techniques to approximate deterministic computer analysis codes. We conclude with recommendations for the appropriate use of statistical approximation techniques in given situations, and how common pitfalls can be avoided.

/pdf/metamodels-for-computer-based-engineering-design-survey-and-382x1fki1s.pdf

Metamodels for Computer-Based Engineering Design: Survey and Recommendations

Latin hypercube sampling and the propagation of uncertainty in analyses of complex systems

Introduction to response surface methodology matrix algebra, least squares, the analysis of variance, and principles of experimental design first-order models and designs second-order models and designs determining optimum conditions methods of estimating response surfaces that rival least squares based on the integrated mean squared error criterion analysis of multiresponse experiments response surface models with block effects mixture designs and analyses nonlinear response surface models Taguchi's robust parameter design additional topics and some directions for future research. Appendix: solutions to selected exercises.

Response surfaces : designs and analyses

The purpose of this article is to provide a survey of the various stages in the development of response surface methodology RSM. The coverage of these stages is organized in three parts that describe the evolution of RSM since its introduction in the early 1950s. Part I covers the period, 1951-1975, during which the so-called classical RSM was developed. This includes a review of basic experimental designs for fitting linear response surface models, in addition to a description of methods for the determination of optimum operating conditions. Part II, which covers the period, 1976-1999, discusses more recent modeling techniques in RSM, in addition to a coverage of Taguchi's robust parameter design and its response surface alternative approach. Part III provides a coverage of further extensions and research directions in modern RSM. This includes discussions concerning response surface models with random effects, generalized linear models, and graphical techniques for comparing response surface designs. Copyright © 2010 John Wiley & Sons, Inc.

Response Surface Methodology.

Response surface methodology

Response sarfxe methodology (RSM) is a collection of tools developed in the 1950s for the purpose of determining optimum operating conditions in applications in the chemical industry. This article reviews the progrrss of RSM in the general areas of experimental design and analysis and indicates how its role has been affected by advanccs in other fields of applied statistics. Current areas of research in RSM are highlighted. and areas for future research are discussed.

https://www.jstor.org/stable/pdfplus/1268813.pdf

Response surface methodology: 1966–1988

An algorithm is developed for the simultaneous optimization of several response functions that depend on the same set of controllable variables and are adequately represented by polynomial regression models of the same degree. The data are first checked for linear dependencies among the responses. If such dependencies exist, a basic set of responses among which no linear functional relationships exist is chosen and used in developing a function that measures the distance of the vector of estimated responses from the estimated “ideal” optimum. This distance function permits the user to account for the variances and covariances of the estimated responses and for the random error variation associated with the estimated ideal optimum. Suitable operating conditions for the simultaneous optimization of the responses are specified by minimizing the prescribed distance function over the experimental region. An extension of the optimization procedure to mixture experiments is also given and the method is illustrat...

André I. Khuri

Papers

Response surfaces : designs and analyses

Response Surface Methodology.

Response surface methodology

Response surface methodology: 1966–1988

Simultaneous Optimization of Multiple Responses Represented by Polynomial Regression Functions