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Andreas Scorilas
Researcher at National and Kapodistrian University of Athens
Publications - 429
Citations - 14973
Andreas Scorilas is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Cancer & Gene. The author has an hindex of 63, co-authored 395 publications receiving 13310 citations. Previous affiliations of Andreas Scorilas include University of Toronto & National Centre of Scientific Research "Demokritos".
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Journal ArticleDOI
Overexpression of matrix-metalloproteinase-9 in human breast cancer: a potential favourable indicator in node-negative patients.
Andreas Scorilas,Andreas Karameris,Niki Arnogiannaki,Alexandros Ardavanis,P Bassilopoulos,Theoni Trangas,Maroulio Talieri +6 more
TL;DR: MMP-9 status was compared with the concentration of cytosolic Cathepsin-D and with other established prognostic factors, in terms of disease free survival and overall survival and it is suggested that M MP-9 may be an independent favourable prognostic factor in node-negative breast cancer patients.
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BCL2 family of apoptosis-related genes: functions and clinical implications in cancer.
TL;DR: Current knowledge of the function and molecular characteristics of a series of classic but also newly discovered genes of the BCL2 family are described, providing the basis for earlier and more accurate cancer diagnosis, prognosis and therapeutic intervention that targets the apoptosis pathways.
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Human Kallikrein 6 (hK6): A New Potential Serum Biomarker for Diagnosis and Prognosis of Ovarian Carcinoma
Eleftherios P. Diamandis,Andreas Scorilas,S. Fracchioli,Marleen Van Gramberen,Henk W.A. de Bruijn,Alfthan Henrik,Antoninus Soosaipillai,Linda Grass,George M. Yousef,Ulf-Håkan Stenman,Marco Massobrio,Ate G.J. van der Zee,Ignace Vergote,Dionyssios Katsaros +13 more
TL;DR: Serum hK6 concentration seems to be a new biomarker for ovarian carcinoma and may have value for disease diagnosis and prognosis and is a powerful predictor of disease-free and overall survival in both univariate and multivariate analyses.
Journal ArticleDOI
Genomic organization of the human kallikrein gene family on chromosome 19q13.3-q13.4.
George M. Yousef,George M. Yousef,Albert Chang,Albert Chang,Andreas Scorilas,Andreas Scorilas,Eleftherios P. Diamandis,Eleftherios P. Diamandis +7 more
TL;DR: Comparative analysis of genes located in this area, provides strong evidence that the human kallikrein gene family locus on chromosome 19 is considerably larger than previously thought, containing at least fifteen genes.
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The Role of BCL2 Family of Apoptosis Regulator Proteins in Acute and Chronic Leukemias
Flora Tzifi,Christina Economopoulou,Dimitrios Gourgiotis,Alexandros Ardavanis,Sotirios G. Papageorgiou,Andreas Scorilas +5 more
TL;DR: Current knowledge on the role of BCL2 apoptosis regulator proteins in acute and chronic leukemias is described to lead to the design of new therapies which may improve patients' survival.