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Brian H. Nathanson
Researcher at Yale University
Publications - 157
Citations - 3820
Brian H. Nathanson is an academic researcher from Yale University. The author has contributed to research in topics: Medicine & Retrospective cohort study. The author has an hindex of 32, co-authored 132 publications receiving 3104 citations. Previous affiliations of Brian H. Nathanson include Penn State Milton S. Hershey Medical Center.
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Journal ArticleDOI
Association between the choice of IV crystalloid and in-hospital mortality among critically ill adults with sepsis*.
Karthik Raghunathan,Andrew D. Shaw,Brian H. Nathanson,Til Stürmer,Alan M. Brookhart,Mihaela S. Stefan,Soko Setoguchi,Chris Beadles,Peter K. Lindenauer +8 more
TL;DR: Among critically ill adults with sepsis, resuscitation with balanced fluids was associated with a lower risk of in-hospital mortality, and if confirmed in randomized trials, this finding could have significant public health implications, as crystalloid resuscitation is nearly universal in sepsi.
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Assessing contemporary intensive care unit outcome: an updated Mortality Probability Admission Model (MPM0-III).
Thomas L. Higgins,Daniel Teres,Wayne S. Copes,Brian H. Nathanson,Maureen Stark,Andrew A. Kramer +5 more
TL;DR: MPM0-II risk factors remain relevant in predicting ICU outcome, but the 1993 model significantly overpredicts mortality in contemporary practice, and two factors have been added to MPM0-III: “full code” resuscitation status at ICU admission, and “zero factor”.
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The relationship between ICU hypotension and in-hospital mortality and morbidity in septic patients.
Kamal Maheshwari,Brian H. Nathanson,Sibyl H. Munson,VS Khangulov,Mitali Stevens,Hussain Badani,Ashish Khanna,Daniel I. Sessler +7 more
TL;DR: Risks for mortality, AKI, and myocardial injury were apparent at 85 mmHg, and for mortality and AKI risk progressively worsened at lower thresholds, and Maintaining MAP well above 65 mmHg may be prudent in septic ICU patients.
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Pre-resuscitation factors associated with mortality in 49,130 cases of in-hospital cardiac arrest: a report from the National Registry for Cardiopulmonary Resuscitation.
TL;DR: Predictive pre-resuscitation factors may supplement patient-specific information available at bedside to assist in revising resuscitation plans during the patient's hospitalization.
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Carbapenem resistance, inappropriate empiric treatment and outcomes among patients hospitalized with Enterobacteriaceae urinary tract infection, pneumonia and sepsis.
TL;DR: In this large US database, the prevalence of CRE among patients with Enterobacteriaceae UTI, pneumonia or sepsis was comparable to other national estimates, and infection with CRE was associated with a four-fold increased risk of receiving IET, which in turn increased mortality, LOS and costs.