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Carmen Sandi
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 274
Citations - 16073
Carmen Sandi is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Neural cell adhesion molecule & Hippocampus. The author has an hindex of 67, co-authored 257 publications receiving 13723 citations. Previous affiliations of Carmen Sandi include MIND Institute & Cajal Institute.
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Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
Dongryeol Ryu,Laurent Mouchiroud,Pénélope Andreux,Elena Katsyuba,Norman Moullan,Amandine A. Nicolet‐dit‐Félix,Evan G. Williams,Pooja Jha,Giuseppe Lo Sasso,Damien Huzard,Patrick Aebischer,Carmen Sandi,Chris Rinsch,Johan Auwerx +13 more
TL;DR: Urolithin A is identified as a first-in-class natural compound that induces mitophagy both in vitro and in vivo following oral consumption and prevents the accumulation of dysfunctional mitochondria with age and extended lifespan in C. elegans and rodents.
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Stress and memory: behavioral effects and neurobiological mechanisms.
TL;DR: High stress levels, whether intrinsic or extrinsic, tend to facilitate Pavlovian conditioning (in a linear-asymptotic manner), while being deleterious for spatial/explicit information processing (which with regard to intrinsic stress levels follows an inverted U-shape effect).
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Experience-dependent facilitating effect of corticosterone on spatial memory formation in the water maze
TL;DR: This work indicates a facilitating corticosterone action, during the post‐training period, on the neural mechanisms determining the strength of information storage under acute, physiological conditions.
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Stress and the social brain: behavioural effects and neurobiological mechanisms
Carmen Sandi,József Haller +1 more
TL;DR: Research in animals and humans has revealed some of the structural, functional and molecular changes in the brain that underlie the effects of stress on social behaviour and will have implications both for the clinic and for society.
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Gene expression across mammalian organ development
Margarida Cardoso-Moreira,Margarida Cardoso-Moreira,Jean Halbert,Delphine Valloton,Britta Velten,C. T. Chen,Yi Shao,Angélica Liechti,Kelly Ascencao,Coralie Rummel,Svetlana Ovchinnikova,Pavel V. Mazin,Pavel V. Mazin,Ioannis Xenarios,Keith Harshman,Matthew Mort,David Neil Cooper,Carmen Sandi,Michael J. Soares,Michael J. Soares,Paula G. Ferreira,Sandra Afonso,Miguel Carneiro,James M. A. Turner,John L. VandeBerg,Amir Fallahshahroudi,Per Jensen,R. Behr,Steven Lisgo,Susan Lindsay,Philipp Khaitovich,Philipp Khaitovich,Philipp Khaitovich,Wolfgang Huber,Julie C. Baker,Simon Anders,Yong Zhang,Henrik Kaessmann +37 more
TL;DR: It is found that the breadth of gene expression and the extent of purifying selection gradually decrease during development, whereas the amount of positive selection and expression of new genes increase during development.