C
Celeste Scotti
Researcher at University of Milan
Publications - 43
Citations - 2326
Celeste Scotti is an academic researcher from University of Milan. The author has contributed to research in topics: Cartilage & Tissue engineering. The author has an hindex of 21, co-authored 40 publications receiving 2058 citations. Previous affiliations of Celeste Scotti include University Hospital of Basel.
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Journal ArticleDOI
Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering
Celeste Scotti,Beatrice Tonnarelli,Adam Papadimitropoulos,Arnaud Scherberich,Stefan Schaeren,Alexandra Schauerte,Javier Lopez-Rios,Rolf Zeller,Andrea Barbero,Ivan Martin +9 more
TL;DR: This study reveals the capacity of human MSC to generate bone tissue via an endochondral program and provides a valid model to study mechanisms governing bone development and could generate advanced grafts for bone regeneration by invoking a “developmental engineering” paradigm.
Journal ArticleDOI
Engineering of a functional bone organ through endochondral ossification.
Celeste Scotti,Elia Piccinini,Hitoshi Takizawa,Atanas Todorov,Paul Bourgine,Adam Papadimitropoulos,Andrea Barbero,Markus G. Manz,Ivan Martin +8 more
TL;DR: The generation by appropriately instructed hMSC of an ectopic “bone organ” with a size, structure, and functionality comparable to native bones is reported, providing a model useful for fundamental and translational studies of bone morphogenesis and regeneration, as well as for the controlled manipulation of hematopoietic stem cell niches in physiology and pathology.
Journal ArticleDOI
One-Step Cartilage Repair with Bone Marrow Aspirate Concentrated Cells and Collagen Matrix in Full-Thickness Knee Cartilage Lesions Results at 2-Year Follow-up
Alberto Gobbi,Georgios Karnatzikos,Celeste Scotti,Vivek Mahajan,Laura Mazzucco,Brunella Grigolo +5 more
TL;DR: 1-step surgery with BMAC and collagen I/III matrix could be a viable technique in the treatment of grade IV knee chondral lesions and showed significant improvement in all scores at final follow-up.
Journal ArticleDOI
The Benefit of Synthetic Versus Biological Patch Augmentation in the Repair of Posterosuperior Massive Rotator Cuff Tears: A 3-Year Follow-up Study
Pietro Ciampi,Celeste Scotti,Alessandro Nonis,Matteo Vitali,Clelia Di Serio,Giuseppe M. Peretti,Gianfranco Fraschini +6 more
TL;DR: Polypropylene patch augmentation of rotator cuff repair was demonstrated to significantly improve the 36-month outcome in terms of function, strength, and retear rate.
Journal ArticleDOI
Meniscus repair and regeneration: review on current methods and research potential.
TL;DR: The clinical need for meniscus regeneration strategies will be explained, and past and current experimental studies on meniscal fibrocartilage regeneration will be reported.