C
Chin Kai Meng
Researcher at Yale University
Publications - 6
Citations - 10227
Chin Kai Meng is an academic researcher from Yale University. The author has contributed to research in topics: Electrospray ionization & Ion. The author has an hindex of 6, co-authored 6 publications receiving 9896 citations.
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Journal ArticleDOI
Electrospray ionization for mass spectrometry of large biomolecules
TL;DR: Spectra have been obtained for biopolymers including oligonucleotides and proteins, the latter having molecular weights up to 130,000, with as yet no evidence of an upper limit.
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Electrospray ionization–principles and practice
TL;DR: Electrospray (E S ) ionization has recently shown itself capable of producing intact ions, with multiple charges, from remarkably large, complex, and fragile parent species as mentioned in this paper, which is the state-of-the-art in mass spectrometric analysis.
Journal ArticleDOI
Electrospray Ionization for Mass Spectrometry of Large Biomolecules
TL;DR: In this article, the power and elegance of mass spectrometric analysis applicable to the large and fragile polar molecules that play such vital roles in biological systems was demonstrated. But the technique was not suitable for the analysis of complex biological systems.
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Interpreting mass spectra of multiply charged ions
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Formation of charged clusters during electrospray ionization of organic solute species
Chin Kai Meng,John B. Fenn +1 more
TL;DR: In this article, the number and size of these cluster ions increased markedly with an increase in the initial solute concentration, and when co-solutes consisting of acids, salts or bases were present, at up to millimolar concentrations in the original solution, clustering was often strongly suppressed, especially by strong acids and their salts.