C
Christine Pfeifle
Researcher at Max Planck Society
Publications - 9
Citations - 3351
Christine Pfeifle is an academic researcher from Max Planck Society. The author has contributed to research in topics: Regulation of gene expression & Drosophila embryogenesis. The author has an hindex of 8, co-authored 9 publications receiving 3148 citations. Previous affiliations of Christine Pfeifle include Ludwig Maximilian University of Munich.
Papers
More filters
Journal ArticleDOI
A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback.
Diethard Tautz,Christine Pfeifle +1 more
TL;DR: A non-radioactive in situ hybridization technique for the localization of RNA in whole mount Drosophila embryos and revealed translational control of the maternally derived hb mRNA, which was difficult to detect by conventional techniques.
Journal ArticleDOI
Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program
Laufey Geirsdottir,Eyal David,Hadas Keren-Shaul,Assaf Weiner,Stefan Cornelius Bohlen,Jana Neuber,Adam Balic,Amir Giladi,Fadi Sheban,Charles-Antoine Dutertre,Christine Pfeifle,Francesca Peri,Antonella Raffo-Romero,Jacopo Vizioli,Kaspar Matiasek,Christian Scheiwe,Stephan Meckel,Kerstin Mätz-Rensing,Franziska van der Meer,Finnbogi Rutur Thormodsson,Christine Stadelmann,Noga Zilkha,Tali Kimchi,Florent Ginhoux,Igor Ulitsky,Daniel Erny,Ido Amit,Marco Prinz +27 more
TL;DR: This study finds that microglia express a conserved core gene program of orthologous genes from rodents to humans, including ligands and receptors associated with interactions between glia and neurons, which provides an essential resource of conserved and divergent microglian pathways across evolution.
Journal ArticleDOI
A morphogenetic gradient of hunchback protein organizes the expression of the gap genes Kruppel and knirps in the early Drosophila embryo
TL;DR: Evidence is reported to support the hypothesis that posterior segmentation might not directly depend on maternal positional cues, but be solely organized at the zygotic level and show that the hb protein itself is crucially involved in organizing abdominal segmentation.
Journal ArticleDOI
Posterior segmentation of the Drosophila embryo in the absence of a maternal posterior organizer gene
TL;DR: Absence of both repressors of hunchback results in normal embryos, indicating that posterior segmentation may not directly require maternal determinants.
Journal ArticleDOI
Genomic resources for wild populations of the house mouse, Mus musculus and its close relative Mus spretus
Bettina Harr,Emre Karakoc,Rafik Neme,Meike Teschke,Christine Pfeifle,Željka Pezer,Hiba Babiker,Miriam Linnenbrink,Inka Montero,Rick J. Scavetta,Mohammad Reza Abai,Marta Puente Molins,Mathias Schlegel,Rainer G. Ulrich,Janine Altmüller,Marek Franitza,Anna B. S. Büntge,Sven Künzel,Diethard Tautz +18 more
TL;DR: Wild populations of the house mouse (Mus musculus) represent the raw genetic material for the classical inbred strains in biomedical research and are a major model system for evolutionary biology and whole genome sequencing data are provided.