C
Cléa Melenotte
Researcher at Aix-Marseille University
Publications - 72
Citations - 1746
Cléa Melenotte is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Coxiella burnetii & Q fever. The author has an hindex of 13, co-authored 61 publications receiving 940 citations. Previous affiliations of Cléa Melenotte include French Institute of Health and Medical Research & Institut de recherche pour le développement.
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Journal ArticleDOI
From Q Fever to Coxiella burnetii Infection: a Paradigm Change.
Carole Eldin,Cléa Melenotte,Oleg Mediannikov,Eric Ghigo,Matthieu Million,Sophie Edouard,Jean-Louis Mege,Max Maurin,Didier Raoult +8 more
TL;DR: All the progress made over the last 20 years on this topic are reviewed, including the breaking of the old dichotomy between “acute” and “chronic” Q fever and the achievement of determining the genome sequences of several strains of this species and comparative genomic analyses.
Journal ArticleDOI
Immune responses during COVID-19 infection
Cléa Melenotte,Aymeric Silvin,Anne Gaëlle Goubet,Imran Lahmar,Agathe Dubuisson,Alimuddin Zumla,Didier Raoult,Didier Raoult,Mansouria Merad,Bertrand Gachot,Clémence Hénon,Eric Solary,Michaela Fontenay,Fabrice Andre,Markus Maeurer,Giuseppe Ippolito,Mauro Piacentini,Fu-Sheng Wang,Florent Ginhoux,Florent Ginhoux,Florent Ginhoux,Aurélien Marabelle,Guido Kroemer,Lisa Derosa,Laurence Zitvogel +24 more
TL;DR: In innate and cognate immune responses underlying protective or deleterious immune reactions against these pathogenic coronaviruses are discussed, including immune responses to SARS-CoV2.
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Natural history of COVID-19 and therapeutic options.
Philippe Gautret,Matthieu Million,Pierre-André Jarrot,Laurence Camoin-Jau,Philippe Colson,Florence Fenollar,Marc Leone,Bernard La Scola,Christian Devaux,Christian Devaux,Jean Gaubert,Jean-Louis Mege,Joana Vitte,Cléa Melenotte,Jean-Marc Rolain,Philippe Parola,Jean-Christophe Lagier,Philippe Brouqui,Didier Raoult +18 more
TL;DR: In this article, the authors review the literature and provide an overview of the current state of knowledge regarding the natural history of and therapeutic options for COVID-19, including antivirals, oxygen therapy, immunomodulators, anticoagulants and prolonged mechanical treatment.
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The immuno-oncological challenge of COVID-19
Lisa Derosa,Lisa Derosa,Lisa Derosa,Cléa Melenotte,Franck Griscelli,Franck Griscelli,Bertrand Gachot,Bertrand Gachot,Aurélien Marabelle,Aurélien Marabelle,Aurélien Marabelle,Guido Kroemer,Laurence Zitvogel +12 more
TL;DR: Why those with cancer are at higher risk of severe CO VID-19 are discussed, immune responses that confer protective or adverse reactions to this disease are described and which antineoplastic therapies may either increase COVID-19 vulnerability or have a dual therapeutic effect on cancer and COVID the virus.
Journal ArticleDOI
B-cell non-Hodgkin lymphoma linked to Coxiella burnetii
Cléa Melenotte,Matthieu Million,Gilles Audoly,Audrey Gorse,Herve Dutronc,Gauthier Roland,Michal Dekel,Asunción Moreno,Serge Cammilleri,Maria Patrizia Carrieri,Camelia Protopopescu,Philippe Ruminy,Hubert Lepidi,Bertrand Nadel,Jean-Louis Mege,Luc Xerri,Didier Raoult +16 more
TL;DR: Results suggest that C burnetii should be added to the list of bacteria that promote human B-cell non-Hodgkin lymphoma, possibly by the infection of pDCs and IL10 overproduction.