C
Cornelis J.H. van de Velde
Researcher at Leiden University Medical Center
Publications - 537
Citations - 42333
Cornelis J.H. van de Velde is an academic researcher from Leiden University Medical Center. The author has contributed to research in topics: Cancer & Breast cancer. The author has an hindex of 89, co-authored 511 publications receiving 35710 citations. Previous affiliations of Cornelis J.H. van de Velde include Leiden University.
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Journal ArticleDOI
Preoperative Radiotherapy Combined with Total Mesorectal Excision for Resectable Rectal Cancer
Ellen Kapiteijn,Corrie A.M. Marijnen,Iris D. Nagtegaal,Hein Putter,W.H. Steup,Theo Wiggers,Harm J. T. Rutten,Lars Påhlman,Bengt Glimelius,J. Han van Krieken,J.W.H. Leer,Cornelis J.H. van de Velde +11 more
TL;DR: In this article, the authors conducted a multicenter, randomized trial to determine whether the addition of preoperative radiotherapy increases the benefit of total mesorectal excision, and the overall rate of survival at two years among the eligible patients was 82.0 percent in the group assigned to both radiotherapy and surgery.
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Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer: 12-year follow-up of the multicentre, randomised controlled TME trial
Willem van Gijn,Carrie A. M. Marijnen,Iris D. Nagtegaal,Elma Meershoek-Klein Kranenbarg,Hein Putter,Theo Wiggers,Harm J. T. Rutten,Lars Påhlman,Bengt Glimelius,Cornelis J.H. van de Velde +9 more
TL;DR: Preoperative short-term radiotherapy significantly improved 10-year survival in patients with a negative circumferential margin and TNM stage III, and future staging techniques should offer possibilities to select patient groups for which the balance between benefits and side-effects will result in sufficiently large gains.
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Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial
Ilfet Songun,Hein Putter,Elma Meershoek-Klein Kranenbarg,M. Sasako,Cornelis J.H. van de Velde +4 more
TL;DR: After a median follow-up of 15 years, D2 lymphadenectomy is associated with lower locoregional recurrence and gastric-cancer-related death rates than D1 surgery and a safer, spleen-preserving D2 resection technique is currently available in high-volume centres.
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Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial
M. Donker,Geertjan van Tienhoven,Marieke E. Straver,P. Meijnen,Cornelis J.H. van de Velde,Robert E. Mansel,Luigi Cataliotti,A. Helen Westenberg,Jean H. G. Klinkenbijl,Lorenzo Orzalesi,Willem H. Bouma,Huub van der Mijle,Grard A. P. Nieuwenhuijzen,Sanne C. Veltkamp,Leen Slaets,Nicole Duez,Peter W. de Graaf,Thijs van Dalen,A. Marinelli,Herman Rijna,Marko Snoj,Nigel J Bundred,Jos W. S. Merkus,Yazid Belkacemi,Patrick Petignat,Dominic A.X. Schinagl,Corneel Coens,Carlo Messina,Jan Bogaerts,Emiel J. Th. Rutgers +29 more
TL;DR: The AMAROS trial as discussed by the authors evaluated axillary lymph node dissection and axillary radiotherapy for T1-2 primary breast cancer and no palpable lymphadenopathy patients with positive sentinel nodes.
Journal ArticleDOI
The TME Trial After a Median Follow-Up of 6 Years: Increased Local Control but No Survival Benefit in Irradiated Patients With Resectable Rectal Carcinoma
Koen C.M.J. Peeters,Corrie A.M. Marijnen,Iris D. Nagtegaal,Elma Meershoek – Klein Kranenbarg,Hein Putter,Theo Wiggers,Harm J. T. Rutten,Lars Påhlman,Bengt Glimelius,Jan Willem H. Leer,Cornelis J.H. van de Velde +10 more
TL;DR: There is a persisting overall effect of preoperative short-term radiotherapy on local control in patients with clinically resectable rectal cancer, however, there is no effect on overall survival.