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Daniel B.F. Saris
Researcher at Mayo Clinic
Publications - 216
Citations - 10017
Daniel B.F. Saris is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Cartilage & Osteoarthritis. The author has an hindex of 50, co-authored 195 publications receiving 8315 citations. Previous affiliations of Daniel B.F. Saris include Utrecht University & University of Rochester.
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Journal ArticleDOI
Characterized Chondrocyte Implantation Results in Better Structural Repair When Treating Symptomatic Cartilage Defects of the Knee in a Randomized Controlled Trial Versus Microfracture
Daniel B.F. Saris,Johan Vanlauwe,Jan Victor,Miroslav Hašpl,Michael Bohnsack,Yves Fortems,Bruno Vandekerckhove,K. Frederik Almqvist,Toon Claes,F. Handelberg,Koen Lagae,Jan Van Der Bauwhede,Hilde Vandenneucker,K. Gie Auw Yang,Mislav Jelić,René Verdonk,Nancy Veulemans,Johan Bellemans,Frank P. Luyten +18 more
TL;DR: One year after treatment, characterized chondrocyte implantation was associated with a tissue regenerate that was superior to that after microfracture, and the superior structural outcome may result in improved long-term clinical benefit with characterized chontological implantation.
Journal ArticleDOI
Treatment of Symptomatic Cartilage Defects of the Knee Characterized Chondrocyte Implantation Results in Better Clinical Outcome at 36 Months in a Randomized Trial Compared to Microfracture
Daniel B.F. Saris,Johan Vanlauwe,Jan Victor,Karl Almqvist,René Verdonk,Johan Bellemans,Frank P. Luyten +6 more
TL;DR: Characterized chondrocyte implantation for the treatment of articular cartilage defects of the femoral condyles of the knee results in significantly better clinical outcome at 36 months in a randomized trial compared with MF.
Journal ArticleDOI
Extracellular matrix scaffolds for cartilage and bone regeneration.
Kim E M Benders,P. René van Weeren,Stephen F. Badylak,Daniel B.F. Saris,Daniel B.F. Saris,Wouter J.A. Dhert,Jos Malda +6 more
TL;DR: The rationale for using ECM-based approaches for different regenerative purposes is described and the application of ECM for cartilage or osteochondral repair is details.
Journal ArticleDOI
International Cartilage Repair Society (ICRS) and Oswestry macroscopic cartilage evaluation scores validated for use in Autologous Chondrocyte Implantation (ACI) and microfracture.
M.P.J. van den Borne,Natasja J H Raijmakers,Johan Vanlauwe,Jan Victor,S.N. de Jong,Johan Bellemans,Daniel B.F. Saris +6 more
TL;DR: The ICRS and OAS are reliable and relevant scores that are now both validated for macroscopic evaluation of cartilage repair as a research tool.
Journal ArticleDOI
Matrix-Applied Characterized Autologous Cultured Chondrocytes Versus Microfracture Two-Year Follow-up of a Prospective Randomized Trial
Daniel B.F. Saris,Andrew Price,Wojciech Widuchowski,Marion Bertrand-Marchand,Jacob Caron,Jon Olav Drogset,Pieter J. Emans,Ales Podskubka,A.I. Tsuchida,Sven Kili,David W. Levine,Mats Brittberg +11 more
TL;DR: The treatment of symptomatic cartilage knee defects ≥3 cm2 in size using MACI was clinically and statistically significantly better than with MFX, with similar structural repair tissue and safety, in this heterogeneous patient population.