David H. Harter

TL;DR: Treatment of Glioblastoma multiforme remains extremely challenging, and continued research and development of targeted therapies, based on a detailed understanding of molecular pathogenesis can reasonably be expected to yield improved outcomes for patients with GBM.

TL;DR: In this article, a theory of ultrashort-pulse second-harmonic generation (SHG) in materials with longitudinally non-uniform quasi-phase-matching (QPM) gratings was presented.

TL;DR: In vitro studies with sorafenib indicate that this effect of unexpected and unprecedented acceleration of tumor growth in children with PLGA, irrespective of NF1 or tumor BRAF status, is likely related to paradoxical ERK activation.

TL;DR: A diode-pumped system for optical parametric generation of wavelength-tunable femtosecond pulses is demonstrated and saturated single-pass parametric energy conversion of 38% has been achieved with only 220 nJ of pump inside the crystal.

TL;DR: A parametric chirped pulse amplification system in which femtosecond pulses from a mode-locked Er-doped fiber laser system are amplified to 1-mJ energies in a single pass by use of a 5-mm-long periodically poled LiNbO(3) (PPLN) crystal, demonstrating that limitations associated with a low optical-damage threshold for long pump pulses can be overcome.