In recent years, acupuncture has increasingly being integrated into pediatric health care. It was used on ~150,000 children (0.2%). We aim to update the evidence for the efficacy and safety of acupuncture for children and evaluate the methodological qualities of these studies to improve future research in this area. We included 24 systematic reviews, comprising 142 randomized controlled trials (RCTs) with 12,787 participants. Only 25% (6/24) reviews were considered to be high quality (10.00 ± 0.63). High-quality systematic reviews and Cochrane systematic reviews tend to yield neutral or negative results (P = 0.052, 0.009 respectively). The efficacy of acupuncture for five diseases (Cerebral Palsy (CP), nocturnal enuresis, tic disorders, amblyopia, and pain reduction) is promising. It was unclear for hypoxic ischemic encephalopathy, attention deficit hyperactivity disorder, mumps, autism spectrum disorder (ASD), asthma, nausea/vomiting, and myopia. Acupuncture is not effective for epilepsy. Only six reviews reported adverse events (AEs) and no fatal side effects were reported. The efficacy of acupuncture for some diseases is promising and there have been no fatal side effects reported. Further high-quality studies are justified, with five diseases in particular as research priorities.

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Efficacy and safety of acupuncture in children: an overview of systematic reviews

Acupuncture and electroacupuncture for anxiety disorders: A systematic review of the clinical research.

// Weiwei Tao 1, 2, 3, # , Xi Luo 1, 2, # , Bai Cui 1, 2, # , Dapeng Liang 1, 2 , Chunli Wang 1, 2 , Yangyang Duan 4 , Xiaofen Li 5 , Shiyu Zhou 6 , Mingjie Zhao 7 , Yi Li 8 , Yumin He 9 , Shaowu Wang 4 , Keith W. Kelley 10, 11 , Ping Jiang 12 , Quentin Liu 1, 2 1 Institute of Cancer Stem Cell, Cancer Center, Dalian Medical University, Dalian, China 2 Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangdong, China 3 College of Nursing, Dalian Medical University, Dalian, China 4 Department of Radiology, Second Affiliated Hospital, Dalian Medical University, Dalian, China 5 School of Public Health, Dalian Medical University, Dalian, China 6 Department of Psychology, Dalian Medical University, Dalian, China 7 Dalian Medical University Magazine, Dalian, China 8 School of Art, Dalian Medical University, Dalian, China 9 Shanghai University of Traditional Chinese Medicine, Shanghai, China 10 Integrative Immunology and Behavior Program, Department of Animal Sciences, College of ACES, Urbana, IL, USA 11 Department of Pathology, College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA 12 Graduate School, Dalian Medical University, Dalian, China # These authors contributed equally to this work Correspondence to: Quentin Liu, e-mail: liuqiang@dlmedu.edu.cn Ping Jiang, e-mail: dywx.2009@163.com Keith W. Kelley, e-mail: kwkelley@illinois.edu Shaowu Wang, e-mail: wsw_2003@163.com Keywords: traditional Chinese medicine, psycho-behavioral interventions, quality of life, cancer, meta-analysis Received: July 15, 2015      Accepted: October 02, 2015      Published: October 15, 2015 ABSTRACT Background: Cancer patients suffer from diverse symptoms, including depression, anxiety, pain, and fatigue and lower quality of life (QoL) during disease progression. This study aimed to evaluate the benefits of Traditional Chinese Medicine psycho-behavioral interventions (TCM PBIs) on improving QoL by meta-analysis. Methods: Electronic literature databases (PubMed, CNKI, VIP, and Wanfang) were searched for randomized, controlled trials conducted in China. The primary intervention was TCM PBIs. The main outcome was health-related QoL (HR QoL) post-treatment. We applied standard meta analytic techniques to analyze data from papers that reached acceptable criteria. Results: The six TCM PBIs analyzed were acupuncture, Chinese massage, Traditional Chinese Medicine five elements musical intervention (TCM FEMI), Traditional Chinese Medicine dietary supplement (TCM DS), Qigong and Tai Chi. Although both TCM PBIs and non-TCM PBIs reduced functional impairments in cancer patients and led to pain relief, depression remission, reduced time to flatulence following surgery and sleep improvement, TCM PBIs showed more beneficial effects as assessed by reducing both fatigue and gastrointestinal distress. In particular, acupuncture relieved fatigue, reduced diarrhea and decreased time to flatulence after surgery in cancer patients, while therapeutic Chinese massage reduced time to flatulence and time to peristaltic sound. Conclusion: These findings demonstrate the efficacy of TCM PBIs in improving QoL in cancer patients and establish that TCM PBIs represent beneficial adjunctive therapies for cancer patients.

Practice of traditional Chinese medicine for psycho-behavioral intervention improves quality of life in cancer patients: A systematic review and meta-analysis

Electroacupuncture regulate hypothalamic-pituitary-adrenal axis and enhance hippocampal serotonin system in a rat model of depression.

The association of dietary inflammatory potential with depression and mental well-being among U.S. adults

Background: Anxiety and depression are high in prevalence, especially in the female population, whose incidence is approximately double that of the male population. In addition, these conditions are difficult to treat and have high relapse rates and medication side-effects. There is evidence to suggest that acupuncture may be an effective treatment modality. Objective: The aim of this review is to summarize the existing evidence on acupuncture as a therapy for anxiety and depression in women and to present a novel method for assessing acupuncture trial quality. Methods: Published randomized controlled trials were included, whereby acupuncture was compared with any control procedure in subjects with anxiety and/or depression. Two authors extracted data independently. A novel acupuncture trial quality-assessment tool was developed to analyze the literature quality. Results: Six articles used the desired inclusion and exclusion criteria. The quality of research varied heavily. Five studies were prop...

David P. Sniezek

Papers

Acupuncture for Treating Anxiety and Depression in Women: A Clinical Systematic Review.

Kiiko Matsumoto's Clinical Strategies in the Spirit of Master Nagano, Vol. 1

Auricular Therapy: A Comprehensive Text: Auricular Phases, Frequencies, and Blockages

Developing Practice Guidelines for Medical Acupuncture