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Diane Warden

Researcher at University of Texas Southwestern Medical Center

Publications -  58
Citations -  6188

Diane Warden is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Major depressive disorder & Randomized controlled trial. The author has an hindex of 33, co-authored 58 publications receiving 5661 citations.

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Medication Augmentation after the Failure of Ssris for Depression

TL;DR: Augmentation of citalopram with either sustained-release bupropion or buspirone appears to be useful in actual clinical settings, including a greater reduction in the number and severity of symptoms and fewer side effects and adverse events.
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Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression.

TL;DR: After unsuccessful treatment with an SSRI, approximately one in four patients had a remission of symptoms after switching to another antidepressant, suggesting any one of the medications in the study provided a reasonable second-step choice for patients with depression.
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The STAR*D project results: A comprehensive review of findings

TL;DR: Prognosis was better at all levels for participants who entered follow-up in remission as opposed to those who entered with response without remission, highlighting the prevalence of treatment-resistant depression and suggesting potential benefit for using more vigorous treatments in the earlier steps.
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Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments: a STAR*D report.

TL;DR: Pharmacologic augmentation was more rapidly effective than cognitive therapy augmentation of citalopram, whereas switching to cognitive therapy was better tolerated than switching to a different antidepressant.
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Combining Medications to Enhance Depression Outcomes (CO-MED): Acute and Long-Term Outcomes of a Single-Blind Randomized Study

TL;DR: Two antidepressant medication combinations were compared with selective serotonin reuptake inhibitor monotherapy to determine whether either combination produced a higher remission rate in first-step acute-phase (12 weeks) and long-term (7 months) treatment.