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Dieter C. Gruenert

Researcher at University of California, San Francisco

Publications -  63
Citations -  5474

Dieter C. Gruenert is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Cell culture & Cystic fibrosis transmembrane conductance regulator. The author has an hindex of 32, co-authored 62 publications receiving 5310 citations. Previous affiliations of Dieter C. Gruenert include Istituto Giannina Gaslini & California Pacific Medical Center.

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Journal ArticleDOI

CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells.

A. L. Cozens, +8 more
- 01 Jan 1994 - 
TL;DR: The successful establishment of a postcrisis SV40 large T-antigen transformed epithelial cell line derived from human bronchial epithelium is described, and this cell line, 16HBE14o- cells, provides a valuable resource for studying the modulation of CFTR and its role in regulation of chloride ion transport in human airway epithelia as well as other aspects of human airways cell biology.
Journal Article

Neutrophil Recruitment by Human IL-17 Via C-X-C Chemokine Release in the Airways

Martti Laan, +7 more
- 15 Feb 1999 - 
TL;DR: It is demonstrated that hIL-17 can specifically and selectively recruit neutrophils into the airways via the release of C-X-C chemokines from bronchial epithelial cells and suggest a novel mechanism linking the activation of T-lymphocytes to recruitment of neutrophil into theAirways.
Journal ArticleDOI

Culture and transformation of human airway epithelial cells

Dieter C. Gruenert, +2 more
- 01 Mar 1995 - 
TL;DR: The implementation of the in vitro cell culture systems that have now been established and the research into optimizing the conditions for the growth of airway epithelial cells have been and will continue to be essential in the development of therapies for airway disease.
Journal ArticleDOI

Cl- channels in CF: lack of activation by protein kinase C and cAMP-dependent protein kinase

Tzyh Chang Hwang, +5 more
- 16 Jun 1989 - 
TL;DR: Channels from normal tissues were activated by both cAMP-dependentprotein kinase and protein kinase C, however, chloride channels from CF patients could not be activated by either kinase.
Journal ArticleDOI

Bioluminescence detection of ATP release mechanisms in epithelia

Amanda L. Taylor, +5 more
- 01 Nov 1998 - 
TL;DR: Results suggest that extracellular ATP may be a constant regulator of epithelial cell function under basal conditions and an autocrine regulator of cell volume under hypotonic conditions, two functions that may be lost in CF and contribute to CF pathophysiology.