Doheon Lee

TL;DR: A protein‐network‐based approach is applied that identifies markers not as individual genes but as subnetworks extracted from protein interaction databases, which provide novel hypotheses for pathways involved in tumor progression.

TL;DR: It is shown that classifiers using pathway activity achieve better performance than classifiers based on individual gene expression, for both simple and complex case-control studies including differentiation of perturbed from non-perturbed cells and subtyping of several different kinds of cancer.

TL;DR: It is shown that PIF3 also negatively regulates chlorophyll biosynthesis by repressing biosynthetic genes in the dark and 4 phytochrome-interacting proteins are required for skotomorphogenesis and phy tochromes activate photomorphogenesis by inhibiting these factors.

TL;DR: ChIP-chip and microarray data indicate that PIL5 inhibits seed germination not just through GA and ABA, but also by coordinating hormone signals and modulating cell wall properties in imbibed seeds.

TL;DR: This work used shotgun metagenomics of mucosal biopsies to explore the microbial communities’ compositions of terminal ileum and large intestine in 5 healthy individuals, and details which species are involved with the tryptophan/indole pathway and the antimicrobial resistance biogeography along the intestine.