D
Dolores C. García-Olmo
Researcher at Hospital Universitario La Paz
Publications - 59
Citations - 1724
Dolores C. García-Olmo is an academic researcher from Hospital Universitario La Paz. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 22, co-authored 58 publications receiving 1526 citations.
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Journal ArticleDOI
Cell-Free Nucleic Acids Circulating in the Plasma of Colorectal Cancer Patients Induce the Oncogenic Transformation of Susceptible Cultured Cells
Dolores C. García-Olmo,Carolina Domínguez,Mariano García-Arranz,Phillipe Anker,Maurice Stroun,José Manuel García-Verdugo,Damián García-Olmo +6 more
TL;DR: The results indicate that plasma from cancer patients is able to transform cultured cells oncogenically, supporting the previously proposed hypothesis of genometastasis.
Journal ArticleDOI
Effects of Long-Term Treatment of Colon Adenocarcinoma With Crocin, a Carotenoid From Saffron (Crocus sativus L.): An Experimental Study in the Rat
Dolores C. García-Olmo,Hans H. Riese,Julio Escribano,Jesús Ontañón,J. A. Fernández,M Atiénzar,Damián García-Olmo +6 more
TL;DR: Long-term treatment with crocin enhances survival selectively in female rats with colon cancer without major toxic effects, and might be related to its strong cytotoxic effect on cultured tumor cells.
Journal ArticleDOI
Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer.
Miguel Reina-Campos,Miguel Reina-Campos,Juan F. Linares,Angeles Duran,Thekla Cordes,Antoine L’Hermitte,Mehmet G. Badur,Munveer S. Bhangoo,Phataraporn K. Thorson,Alicia L. Richards,Tarmo Rooslid,Dolores C. García-Olmo,Syongh Y. Nam-Cha,Antonio S. Salinas-Sánchez,Kenneth Eng,Himisha Beltran,David Scott,Christian M. Metallo,Jorge Moscat,Maria T. Diaz-Meco +19 more
TL;DR: A metabolic vulnerability triggered by PKCλ/ι deficiency in NEPC is uncovered, which offers potentially actionable targets to prevent therapy resistance in PCa.
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Tumor DNA circulating in the plasma might play a role in metastasis. The hypothesis of the genometastasis.
TL;DR: The presence of tumor DNA in plasma is examined using an experimental model in which tumor cells were modified with a genome-associated tag to propose the following hypothesis: Metastases might develop as a result of transfection of susceptible cells in distant target organs with dominant oncogenes that are present in the circulating plasma and are derived from the primary tumor.
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A new bronchoscopic treatment of tracheomediastinal fistula using autologous adipose-derived stem cells
TL;DR: The case history is reported of a patient with a tracheomediastinal fistula resulting from laser treatment of tracheal cancer who was treated by bronchoscopic injection of autologous adipose-derived stem cells suspended in fibrin glue, the first report of treatment oftracheal fistula by autologously derived cell therapy.