Edon Vitaku

TL;DR: This review reports on the top 25 most commonly utilized nitrogen heterocycles found in pharmaceuticals, and reports detailed substitution patterns, highlight common architectural cores, and discuss unusual or rare structures.

TL;DR: The evolution and structural diversity of sulfur and the popular integration of fluorine into drugs introduced over the past 50 years are evaluated and promoted to promote innovative insights into drug development.

TL;DR: Two-dimensional covalent organic frameworks (2D COFs) offer broad monomer scope but are generally isolated as powders comprising aggregated nanometer-scale crystallites, but it is found that 2D COF formation could be controlled using a two-step procedure in which monomers are added slowly to preformed nanoparticle seeds, which should enable a broad exploration of synthetic 2D polymer structures and properties.

TL;DR: The unmodified DAPH-TFP COF exhibited excellent electrical access to its redox sites, even without PEDot functionalization, and outperformed the PEDOT composite of the previously reported anthraquinone-based system.

TL;DR: This method is amenable to both conventional solvothermal conditions and microwave heating, providing similar or even improved materials quality with shorter reaction times, and the high materials quality, scalability, and availability of benzophenone imine monomers are all attractive features of this approach.