E
Emanuel P. Rivers
Researcher at Henry Ford Hospital
Publications - 199
Citations - 20675
Emanuel P. Rivers is an academic researcher from Henry Ford Hospital. The author has contributed to research in topics: Septic shock & Sepsis. The author has an hindex of 54, co-authored 193 publications receiving 19493 citations. Previous affiliations of Emanuel P. Rivers include Edwards Lifesciences Corporation & Henry Ford Health System.
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Journal ArticleDOI
Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock
Emanuel P. Rivers,Bryant Nguyen,Suzanne Havstad,Julie Ressler,Alexandria Muzzin,Bernhard P. Knoblich,Edward L. Peterson,Michael C. Tomlanovich +7 more
TL;DR: This study randomly assigned patients who arrived at an urban emergency department with severe sepsis or septic shock to receive either six hours of early goal-directed therapy or standard therapy (as a control) before admission to the intensive care unit.
Journal ArticleDOI
Early lactate clearance is associated with improved outcome in severe sepsis and septic shock.
H. Bryant Nguyen,Emanuel P. Rivers,Bernhard P. Knoblich,Gordon Jacobsen,Alexandria Muzzin,Julie Ressler,Michael C. Tomlanovich +6 more
TL;DR: Lactate clearance early in the hospital course may indicate a resolution of global tissue hypoxia and is associated with decreased mortality rate, and patients with higher lactate clearance after 6 hrs of emergency department intervention have improved outcome compared with those with lower lactate cleared.
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Coronary perfusion pressure and the return of spontaneous circulation in human cardiopulmonary resuscitation.
Norman A. Paradis,Gerard B. Martin,Emanuel P. Rivers,Mark G. Goetting,Timothy J. Appleton,Marcia Feingold,Richard M. Nowak +6 more
TL;DR: Of variables measured, maximal CPP was most predictive of ROSC, and all CPP measurements were more predictive than was aortic pressure alone, substantiates animal data that indicate the importance of CPP during cardiopulmonary resuscitation.
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Emergency department overcrowding in the United States: an emerging threat to patient safety and public health
TL;DR: The purpose of this review is to describe how ED overcrowding threatens patient safety and public health, and to explore the complex causes and potential solutions for the overcrowding crisis.
Journal ArticleDOI
An Integrated Clinico-Metabolomic Model Improves Prediction of Death in Sepsis
Raymond J. Langley,Raymond J. Langley,Ephraim L. Tsalik,Ephraim L. Tsalik,Jennifer C. van Velkinburgh,Seth W. Glickman,Seth W. Glickman,Brandon J. Rice,Chunping Wang,Bo Chen,Lawrence Carin,Arturo Suarez,Robert P. Mohney,D. Freeman,Mu Wang,Jinsam You,Jacob Wulff,J. Will Thompson,M. Arthur Moseley,Stephanie Reisinger,Brian T. Edmonds,Brian W. Grinnell,David R. Nelson,Darrell L. Dinwiddie,Darrell L. Dinwiddie,Darrell L. Dinwiddie,Neil A. Miller,Neil A. Miller,Carol J. Saunders,Sarah S. Soden,Angela J. Rogers,Lee Gazourian,Laura E. Fredenburgh,Anthony F. Massaro,Rebecca M. Baron,Augustine M.K. Choi,G. Ralph Corey,Geoffrey S. Ginsburg,Charles B. Cairns,Ronny M. Otero,Vance G. Fowler,Emanuel P. Rivers,Christopher W. Woods,Stephen F. Kingsmore,Stephen F. Kingsmore +44 more
TL;DR: A molecular signature, derived from integrated analysis of clinical data, the metabolome, and the proteome in prospective human studies, improved the prediction of death in patients with sepsis, potentially identifying a subset of patients who merit intensive treatment.