E
Erik Henke
Researcher at University of Würzburg
Publications - 54
Citations - 3874
Erik Henke is an academic researcher from University of Würzburg. The author has contributed to research in topics: Progenitor cell & Lipase. The author has an hindex of 26, co-authored 51 publications receiving 3043 citations. Previous affiliations of Erik Henke include University of Stuttgart & Memorial Sloan Kettering Cancer Center.
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Journal ArticleDOI
Tumor entrained neutrophils inhibit seeding in the premetastatic lung
TL;DR: It is demonstrated that neutrophils accumulate in the lung prior to the arrival of metastatic cells in mouse models of breast cancer.
Journal ArticleDOI
Phenotypic diversity and plasticity in circulating neutrophil subpopulations in cancer.
Jitka Y. Sagiv,Janna Michaeli,Simaan Assi,Inbal Mishalian,Hen Kisos,Liran Levy,Pazzit Damti,Delphine Lumbroso,Lola Polyansky,Ronit Vogt Sionov,Amiram Ariel,Avi-Hai Hovav,Erik Henke,Zvi G. Fridlender,Zvi Granot +14 more
TL;DR: This work has identified a heterogeneous subset of low-density neutrophils (LDNs) that appear transiently in self-resolving inflammation but accumulate continuously with cancer progression, providing a mechanistic explanation to mitigate the controversy surrounding neutrophil function in cancer.
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Extracellular Matrix in the Tumor Microenvironment and Its Impact on Cancer Therapy
TL;DR: The current understanding of the physical, cellular, and molecular mechanisms by which the pathological tumor ECM affects the efficiency of radio-, chemo-, and immunotherapy is highlighted.
Journal ArticleDOI
Rapid Chemotherapy-Induced Acute Endothelial Progenitor Cell Mobilization: Implications for Antiangiogenic Drugs as Chemosensitizing Agents
Yuval Shaked,Erik Henke,Jeanine M.L. Roodhart,Patrizia Mancuso,Marlies H.G. Langenberg,Marco Colleoni,Laura G.M. Daenen,Shan Man,Ping Xu,Urban Emmenegger,Terence Tang,Zhenping Zhu,Larry Witte,Robert M. Strieter,Francesco Bertolini,Emile E. Voest,Robert Benezra,Robert S. Kerbel +17 more
TL;DR: It is shown that certain chemotherapy drugs, e.g., paclitaxel, can rapidly induce proangiogenic bone marrow-derived circulating endothelial progenitor (CEP) mobilization and subsequent tumor homing, whereas others do not.
Journal ArticleDOI
Activity of lipases and esterases towards tertiary alcohols: insights into structure-function relationships.
TL;DR: Hydrolytic enzymes are versatile biocatalysts and find increasing applications in organic synthesis and a considerable number of industrial processes using these enzymes have been commercialized.