G
Gerald Weissmann
Researcher at New York University
Publications - 489
Citations - 31041
Gerald Weissmann is an academic researcher from New York University. The author has contributed to research in topics: Superoxide & Inflammation. The author has an hindex of 98, co-authored 489 publications receiving 30587 citations. Previous affiliations of Gerald Weissmann include University of York & Albert Einstein College of Medicine.
Papers
More filters
Journal ArticleDOI
Complement and immunoglobulins stimulate superoxide production by human leukocytes independently of phagocytosis.
TL;DR: Since enhanced O-2 production was stimulated by immune reactants in the absence of phagocytosis, the O-.2 generating system is very likely associated with the external plasma membrane of the polymorphonuclear leukocyte.
Journal ArticleDOI
A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1.
TL;DR: These studies suggest that antagonism by dexamethasone of endotoxin-induced inflammation is a specific instance of the general biological principle that the glucocorticoid receptor is a hormone-dependent regulator of transcription.
Journal ArticleDOI
Release of inflammatory mediators from stimulated neutrophils.
TL;DR: It is known that each injection of serum, white of egg, milk, or fatty matter, is followed by a rather considerable aseptic inflammation at the point at which these substances are introduced.
Journal ArticleDOI
Mechanisms of Lysosomal Enzyme Release from Human Leukocytes II. EFFECTS OF cAMP AND cGMP, AUTONOMIC AGONISTS, AND AGENTS WHICH AFFECT MICROTUBULE FUNCTION
TL;DR: The data suggest that granule movement and acid hydrolase release from leukocyte lysosomes requires intact microtubules and may be modulated by adrenergic and cholinergic agents which appear to provoke changes in concentrations of cyclic nucleotides.
Journal ArticleDOI
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.
TL;DR: Data indicate that adenosine (at concentrations that are present in plasma) acting via cell surface receptors is a specific modulator of superoxide anion generation by neutrophils.