Giorgio Milazzo

TL;DR: It is shown that propane metabolism generated terminal and sub-terminal oxidation products such as 1- and 2-propanol, whereas 1-butanol was the only terminal oxidation product detected from n-butane metabolism.

TL;DR: A review on the recent knowledge accrued on the zinc-dependent HDAC protein family across different species, tissues, and human pathologies, specifically focusing on the role of HDAC inhibitors as anti-cancer agents.

TL;DR: The important roles of lncUSMycN and NonO in regulating N-Myc expression and neuroblastoma oncogenesis are demonstrated and the first evidence that amplification of long noncoding RNA genes can contribute to tumorigenesis is provided.

TL;DR: First insights are provided into the genetic and metabolic mechanisms allowing a Rhodococcus strain to aerobically degrade NAs and the predicted products of the chcpca gene cluster are proposed to be involved in aerobic NA degradation in R. aetherivorans BCP1.

TL;DR: Inhibiting polyamine uptake with the small-molecule drug AMXT 1501, in combination with DFMO, prevented or delayed tumor development in neuroblastoma-prone mice and extended survival in rodent models of established tumors.