Gustave Moonen

TL;DR: Standardized neurobehavioral assessment is a more sensitive means of establishing differential diagnosis in patients with disorders of consciousness when compared to diagnoses determined by clinical consensus.

TL;DR: It is shown that default network connectivity is decreased in severely brain-damaged patients, in proportion to their degree of consciousness impairment, as well as in healthy controls and locked-in syndrome patients.

TL;DR: Results indicate a positive relationship between conscious perception of low-intensity somatosensory stimuli and immediately preceding levels of baseline activity in medial thalamus and the lateral frontoparietal network, respectively, which are thought to relate to vigilance and “external monitoring".

TL;DR: An improved assessment of brain function in coma and related states is not only changing nosology and medical care but also offers a better-documented diagnosis and prognosis and helps to further identify the neural correlates of human consciousness.

TL;DR: It is reported that the multisubunit histone acetyltransferase Elongator complex, which contributes to transcript elongation, also regulates the maturation of projection neurons and it is suggested that a tight regulation of its acetylation underlies thematuration of cortical projection neurons.