G
Gustavo Duque
Researcher at University of Melbourne
Publications - 309
Citations - 10126
Gustavo Duque is an academic researcher from University of Melbourne. The author has contributed to research in topics: Osteoporosis & Sarcopenia. The author has an hindex of 46, co-authored 275 publications receiving 7196 citations. Previous affiliations of Gustavo Duque include University of Sydney & McGill University Health Centre.
Papers
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Aging and bone loss: new insights for the clinician:
TL;DR: New evidence on the pathophysiology of age-related bone loss with emphasis upon the mechanism of action of current osteoporosis treatments is reviewed, including therapeutic approaches to osteoporeosis in the elderly that focus on thePathophysiology and potential reversal of adipogenic shift in bone.
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Statins for Secondary Prevention in Elderly Patients: A Hierarchical Bayesian Meta-Analysis
Jonathan Afilalo,Gustavo Duque,Russell Steele,J. Wouter Jukema,Anton J. M. de Craen,Mark J. Eisenberg +5 more
TL;DR: In this paper, a study was designed to determine whether statins reduce all-cause mortality in elderly patients with coronary heart disease, and the results showed that statins significantly reduced the mortality of elderly patients.
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Osteosarcopenia: where bone, muscle, and fat collide.
TL;DR: It is suggested that when bone mineral density loss is synchronic with decreased muscle mass, strength, and function, it should be interpreted as a single diagnosis of osteosarcopenia, which may be preventable and treatable.
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Age-Related Bone Loss: Old Bone, New Facts
George K. Chan,Gustavo Duque +1 more
TL;DR: The mechanism of programmed cell death, apoptosis, as being an important determinant of aging in bone as well as possible future interventions to prolong the life span of osteoblasts are considered.
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Bone and fat connection in aging bone.
TL;DR: The age-induced mechanisms regulating the predominant differentiation of mesenchymal stem cells into adipocytes will be focused on, and bone marrow fat will be considered as a diagnostic and therapeutic approach to osteoporosis.