Helena Cabral Marques

TL;DR: In this article, a guest inclusion into the apolar CyD cavity is proved by various analytical techniques, including NMR spectroscopy, UV-visible absorption spectrography, optical rotatory dispersion and circular dichroism, fluorescence, infrared/FT-IR spectrographic, thermo-analysis, TLC, mass spectromety, and powder X-ray diffractometry.

TL;DR: The aim of this work was to review the applications of the CDs and their hydrophilic derivatives on the solubility enhancement of poorly water-soluble drugs in order to increase their dissolution rate and get immediate release, as well as their ability to control the release of drugs from solid dosage forms.

TL;DR: In this article, the physicochemical properties of the solid complexes prepared by traditional methods (kneading, freeze-drying and spraydrying) and using a supercritical fluid technology were compared.

TL;DR: Tretino in-UDV is a promising delivery system for tretinoin dermal delivery without promoting skin irritation (unlike other commercial formulations), which is quite advantageous for therapeutic purpose.

TL;DR: In this paper, the effects of preexposure to lycopene on UV-B-irradiated skin cells were investigated, and several parameters were analyzed by FCM and RT-PCR: genotoxicity/clastogenicity by assessing the cell cycle distribution; apoptosis by performing the Annexin-V assay and analyzing gene expression of apoptosis biomarkers; and oxidative stress by ROS quantification.