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Henk J. Groenewegen

Researcher at VU University Medical Center

Publications -  162
Citations -  25746

Henk J. Groenewegen is an academic researcher from VU University Medical Center. The author has contributed to research in topics: Nucleus accumbens & Basal ganglia. The author has an hindex of 72, co-authored 161 publications receiving 24684 citations. Previous affiliations of Henk J. Groenewegen include Netherlands Institute for Neuroscience & VU University Amsterdam.

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Evidence for a multi-compartmental histochemical organization of the nucleus accumbens in the rat

TL;DR: A comparison of the connectivity patterns and neurochemical characteristics of the opioid receptor‐dense compartments in the nucleus accumbens with those in the caudate‐putamen reveals major discrepancies between these two striatal subdivisions.
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Intrinsic connections of the cingulate cortex in the rat suggest the existence of multiple functionally segregated networks.

TL;DR: Topographical and laminar characteristics of intrinsic cingulate connections in the rat, using the anterograde tracers Phaseolus vulgaris-leucoagglutinin and biotinylated dextran amine, demonstrate that rostral areas are primarily interconnected with each other and not with other cingulates areas.
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Anatomical evidence for direct connections between the shell and core subregions of the rat nucleus accumbens.

TL;DR: The intrastriatal projection patterns indicate the existence of lateral inhibitory interactions within, as well as between, shell and core subregions of the nucleus accumbens, and show widespread intra-accumbens projection patterns, including reciprocal projections between specific parts of the shell andcore.
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Connections of the parahippocampal cortex in the cat. V. Intrinsic connections; comments on input/output connections with the hippocampus.

TL;DR: It appears that within the parahippocampal cortex of the cat a framework exists, which is composed of longitudinal and transverse connections, organized according to three principles: Medially directed projections originate mostly in superficial layers, whereas laterally directed fibers come from deep layers.
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Stage-Dependent Nigral Neuronal Loss in Incidental Lewy Body and Parkinson's Disease

TL;DR: The findings cast doubt on the pathogenic role of α‐synuclein aggregates in elderly, but do suggest that the severity of neurodegeneration and local burden of α-synucleIn pathological conditions are closely coupled during disease progression in Parkinson's disease.