H
Hitoshi Asakura
Researcher at Niigata University
Publications - 349
Citations - 9450
Hitoshi Asakura is an academic researcher from Niigata University. The author has contributed to research in topics: Ulcerative colitis & Hepatocellular carcinoma. The author has an hindex of 50, co-authored 329 publications receiving 9087 citations. Previous affiliations of Hitoshi Asakura include Keio University & National Institute of Genetics.
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Journal ArticleDOI
Functional Differences of Anti-T-Cell Antibody in Patients with Systemic Lupus Erythematosus and Ulcerative Colitis
Tohru Abe,Chikao Morimoto,T. Toguchi,M. Kiyotaki,Tsutomu Takeuchi,Jun Koide,Hitoshi Asakura,Masaharu Tsuchiya,Mitsuo Homma +8 more
TL;DR: The functional characteristics of anti‐T‐cell antibody from a selected sub group of patients with ulcerative colitis (UC) were compared with those from patients with SLE, and it is believed that serum from the selected subgroup of Patients with UC reacted with the inducer T‐cell subset.
Journal ArticleDOI
Heterogeneity of p53 Mutational Status in Intramucosal Carcinoma of the Colorectum
Satoshi Yamada,Yoichi Ajioka,Hidenobu Watanabe,Hideki Hashidate,Hideya Takaku,Shinsuke Kazama,Junji Yokoyama,Ken Nishikura,Takato Fujiwara,Hitoshi Asakura +9 more
TL;DR: It is suggested that colorectal carcinomas can be composed of various subclones as regards p53 gene mutation, while the carcinoma is limited to the mucosa, and one of theseSubclones commences invasion to the submucosa after clonal selection, thus generating a monoclonal invasive carcinoma.
Journal ArticleDOI
Sequence analysis of the proximal promoter region of the human α-fetoprotein gene in hepatocellular carcinoma
Kentarou Igarashi,Yutaka Aoyagi,Showgo Ohkoshi,Tsuyoshi Yokota,Shigeki Mori,Tsuyoshi Suda,Tomoteru Kamimura,Hitoshi Asakura +7 more
TL;DR: The results suggest that the extremely proximal promoter region of the AFP gene where glucocorticoid-responsive element and HNF-1 binding sites exist is not responsible for the re-expression of AFP in HCC.
Book ChapterDOI
Role of Interferon -γ-Inducible Protein (IP)-10/ (IP-10/CXCL10) in Ulcerative Colitis; A Review of the Present Status
TL;DR: The role of interferon-γ-inducible protein (IP)-10 (IP10/CXCL10) in the colon of normal condition and UC is reviewed, introducing the recent findings about the effect of neutralization of IP-10 on animal models of UC and the possibility of clinical application of antagonist therapies targeting IP- 10.
Journal ArticleDOI
Prevalence and whole-genome sequence analysis of Campylobacter spp. strains isolated from wild deer and boar in Japan.
Satoshi Morita,Shingo Sato,Soichi Maruyama,Asuka Miyagawa,Kiriko Nakamura,M. Nakamura,Hitoshi Asakura,Hiromu Sugiyama,Shinji Takai,Ken Maeda,Hidenori Kabeya +10 more
TL;DR: In this paper , the prevalence of Campylobacter spp. in wild deer and boar in Japan was investigated, and the authors highlighted the importance of food hygiene in the processing of wild meats for human consumption.