J
J. Scott Weese
Researcher at Ontario Veterinary College
Publications - 337
Citations - 14337
J. Scott Weese is an academic researcher from Ontario Veterinary College. The author has contributed to research in topics: Clostridium difficile & Medicine. The author has an hindex of 61, co-authored 301 publications receiving 12427 citations. Previous affiliations of J. Scott Weese include University of Guelph.
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Journal ArticleDOI
Staphylococcus aureus CC398: Host Adaptation and Emergence of Methicillin Resistance in Livestock
Lance B. Price,Marc Stegger,Henrik Hasman,Maliha Aziz,Jesper Larsen,Paal Skytt Andersen,Talima Pearson,Andrew E. Waters,Jeffrey T. Foster,James M. Schupp,John D. Gillece,Elizabeth M. Driebe,Cindy M. Liu,Cindy M. Liu,Burkhard Springer,Irena Zdovc,Antonio Battisti,Alessia Franco,Jacek Żmudzki,Stefan Schwarz,Patrick Butaye,Eric Jouy,Constança Pomba,M. Concepción Porrero,Raymond Ruimy,Tara C. Smith,D. Ashley Robinson,J. Scott Weese,Carmen Sofia Arriola,Fangyou Yu,Frédéric Laurent,Paul Keim,Paul Keim,Robert Skov,Frank Møller Aarestrup +34 more
TL;DR: The results strongly suggest that livestock-associated MRSA CC398 originated in humans as MSSA, which appears to have undergone a rapid radiation in conjunction with the jump from humans to livestock, where it subsequently acquired tetracycline and methicillin resistance.
Journal ArticleDOI
Frozen vs Fresh Fecal Microbiota Transplantation and Clinical Resolution of Diarrhea in Patients With Recurrent Clostridium difficile Infection: A Randomized Clinical Trial.
Christine H. Lee,Christine H. Lee,Theodore S. Steiner,Elaine O. Petrof,Marek Smieja,Marek Smieja,Diane Roscoe,Anouf Nematallah,J. Scott Weese,Stephen M. Collins,Paul Moayyedi,Mark Crowther,Mark Crowther,Mark J. Ropeleski,Padman Jayaratne,Padman Jayaratne,David Higgins,Yingfu Li,Neil Rau,Peter T. Kim,Peter T. Kim +20 more
TL;DR: Among adults with recurrent or refractory CDI, the use of frozen compared with fresh FMT did not result in worse proportion of clinical resolution of diarrhea, and its use is a reasonable option in this setting.
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Methicillin-resistant Staphylococcus aureus and Staphylococcus pseudintermedius in veterinary medicine.
TL;DR: The relative importance of these staphylococci on different animal species varies, as do the concerns about zoonotic transmission, yet it is clear that both present a challenge to veterinary medicine.
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Clonal spread of methicillin-resistant Staphylococcus pseudintermedius in Europe and North America: an international multicentre study
Vincent Perreten,Kristina Kadlec,Stefan Schwarz,Ulrika Grönlund Andersson,Maria Finn,Christina Greko,Arshnee Moodley,Stephen A. Kania,Linda A. Frank,David A. Bemis,Alessia Franco,Manuela Iurescia,Antonio Battisti,Birgitta Duim,Jaap A. Wagenaar,Engeline van Duijkeren,J. Scott Weese,J. Ross Fitzgerald,Alexandra Rossano,Luca Guardabassi +19 more
TL;DR: Two major clonal MRSP lineages have disseminated in Europe and North America and regardless of their geographical or clonal origin, the isolates displayed resistance to the major classes of antibiotics used in veterinary medicine and thus infections caused by MRSP isolates represent a serious therapeutic challenge.
Journal ArticleDOI
Comparison of the fecal microbiota of healthy horses and horses with colitis by high throughput sequencing of the V3-V5 region of the 16S rRNA gene.
Marcio C. Costa,Luis G. Arroyo,Emma Allen-Vercoe,Henry R. Stämpfli,Peter T. Kim,Amy Sturgeon,J. Scott Weese +6 more
TL;DR: The marked differences in the microbiome between healthy horses and horses with colitis indicate that colitis may be a disease of gut dysbiosis, rather than one that occurs simply through overgrowth of an individual pathogen.