J
Jeremy Sokolove
Researcher at Stanford University
Publications - 111
Citations - 7159
Jeremy Sokolove is an academic researcher from Stanford University. The author has contributed to research in topics: Arthritis & Autoantibody. The author has an hindex of 35, co-authored 108 publications receiving 5702 citations. Previous affiliations of Jeremy Sokolove include United States Department of Veterans Affairs & Veterans Health Administration.
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Journal ArticleDOI
Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis
William H. Robinson,Christin M. Lepus,Christin M. Lepus,Qian Wang,Qian Wang,Harini Raghu,Harini Raghu,Rong Mao,Rong Mao,Tamsin M. Lindstrom,Tamsin M. Lindstrom,Jeremy Sokolove,Jeremy Sokolove +12 more
TL;DR: Osteoarthritis has long been viewed as a degenerative disease of cartilage, but accumulating evidence indicates that inflammation has a critical role in its pathogenesis, and increasing insight into the inflammatory underpinnings of OA holds promise for the development of new, disease-modifying therapies.
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Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations
TL;DR: This review will discuss a wide range of evolving data leading to the current hypotheses regarding the role of immune activation and inflammation in OA onset and progression as this is the joint most well characterized by epidemiologic, imaging, and translational studies investigating the association of inflammation with OA.
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Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis.
Jeremy Sokolove,Jeremy Sokolove,Reuven Bromberg,Reuven Bromberg,Kevin D. Deane,Lauren J. Lahey,Lezlie A. Derber,Piyanka E Chandra,Jess D. Edison,William R. Gilliland,Robert Tibshirani,Jill M. Norris,V. Michael Holers,William H. Robinson,William H. Robinson +14 more
TL;DR: It is observed that the preclinical phase of RA is characterized by an accumulation of multiple autoantibody specificities reflecting the process of epitope spread, and a biomarker profile including autoantsibodies and cytokines which predicts the imminent onset of clinical arthritis is identified.
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Aggregatibacter actinomycetemcomitans–induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis
Maximilian F. Konig,Loreto Abusleme,Jesper Reinholdt,Robert J. Palmer,Ricardo Teles,Ricardo Teles,Kevon Sampson,Antony Rosen,Peter A. Nigrovic,Peter A. Nigrovic,Jeremy Sokolove,Jon T. Giles,Niki M. Moutsopoulos,Felipe Andrade +13 more
TL;DR: It is demonstrated that a particular periodontal pathogen called Aggregatibacter actinomycetemcomitans (Aa) induces changes in neutrophil function, including hypercitrullination of host proteins, an abnormality that is also observed in the joints of patients with rheumatoid arthritis.
Journal ArticleDOI
Periodontitis and Porphyromonas gingivalis in patients with rheumatoid arthritis.
Ted R. Mikuls,Jeffrey B. Payne,Fang Yu,Geoffrey M. Thiele,Richard J. Reynolds,Grant W. Cannon,Jeffrey Markt,David McGowan,Gail S. Kerr,Robert S. Redman,Andreas M. Reimold,Garth R. Griffiths,Mark W. Beatty,Shawneen M. Gonzalez,Debra A. Bergman,Bartlett C. Hamilton,Alan R Erickson,Jeremy Sokolove,William H. Robinson,Clay Walker,Fatiha Chandad,James R. O'Dell +21 more
TL;DR: To examine the degree to which shared risk factors explain the relationship of periodontitis to rheumatoid arthritis (RA) and to determine the associations of PD and Porphyromonas gingivalis with pathologic and clinical features of RA.