John D. F. Hale

TL;DR: In this paper, an updated review of how cationic antimicrobial peptides are able to affect bacterial killing, with a focus on internal targets, is presented, where some peptides clearly act differently and other intracellular target sites have been identified.

TL;DR: The results show that the number of positively charged residues on the polar face and net charge are both important for both antimicrobial activity and hemolytic activity.

TL;DR: The results show that the number of positively charged residues on the polar face and net charge are both important for both antimicrobial activity and hemolytic activity.

TL;DR: It was concluded that S. salivarius M18 can provide oral health benefits when taken regularly and the absence of any significant adverse events supported the safety of the probiotic treatment.

TL;DR: Strain K12, the prototype S. salivarius probiotic, originally introduced to counter Streptococcus pyogenes infections, now has an expanded repertoire of health-promoting applications, and other potential applications include upregulation of immunological defenses against respiratory viral infections and treatment of oral candidosis.