scispace - formally typeset
J

John W. Newcomer

Researcher at Washington University in St. Louis

Publications -  165
Citations -  17721

John W. Newcomer is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Population & Mental illness. The author has an hindex of 60, co-authored 158 publications receiving 16490 citations. Previous affiliations of John W. Newcomer include University of Missouri–St. Louis & Hofstra University.

Papers
More filters
Journal ArticleDOI

Second-Generation (Atypical) Antipsychotics and Metabolic Effects: A Comprehensive Literature Review.

TL;DR: There is no evidence at this time to suggest that ziprasidone and aripiprazole treatment are associated with an increase in risk for diabetes, dyslipidaemia or other adverse effects on glucose or lipid metabolism, but case reports tentatively suggest that substantial weight gain or obesity may not be a factor in up to one-quarter of cases of new-onset diabetes.
Journal ArticleDOI

NMDA receptor hypofunction model of schizophrenia

TL;DR: A version of the NMDA receptor hypofunction hypothesis that has evolved from recent studies pertaining to the neurotoxic and psychotomimetic effects of PCP and related NMDA antagonist drugs is presented.
Journal ArticleDOI

Ketamine-Induced NMDA Receptor Hypofunction as a Model of Memory Impairment and Psychosis

TL;DR: This double-blind, placebo-controlled, randomized, within-subjects comparison of three fixed subanesthetic, steady-state doses of intravenous ketamine in healthy males demonstrated dose-dependent increases in Brief Psychiatric Rating Scale positive and negative symptoms.