J
Jong-Seok Lee
Researcher at Yonsei University
Publications - 300
Citations - 16525
Jong-Seok Lee is an academic researcher from Yonsei University. The author has contributed to research in topics: Video quality & Deep learning. The author has an hindex of 36, co-authored 281 publications receiving 12973 citations. Previous affiliations of Jong-Seok Lee include University of California, Los Angeles & Seoul National University.
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Journal ArticleDOI
Pembrolizumab for the treatment of non-small cell lung cancer
Edward B. Garon,Naiyer A. Rizvi,Rina Hui,Natasha B. Leighl,Ani Sarkis Balmanoukian,Joseph Paul Eder,Amita Patnaik,Charu Aggarwal,Matthew A. Gubens,Leora Horn,Enric Carcereny,Myung-Ju Ahn,Enriqueta Felip,Jong-Seok Lee,Matthew D. Hellmann,Omid Hamid,Jonathan W. Goldman,Jean-Charles Soria,Marisa Dolled-Filhart,Ruth Z. Rutledge,Jin Zhang,Jared Lunceford,Reshma A. Rangwala,Gregory M. Lubiniecki,Charlotte Roach,Kenneth Emancipator,Leena Gandhi +26 more
TL;DR: Pembrolizumab had an acceptable side-effect profile and showed antitumor activity in patients with advanced non-small-cell lung cancer and PD-L1 expression in at least 50% of tumor cells correlated with improved efficacy of pembrolIZumab.
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DEAP: A Database for Emotion Analysis ;Using Physiological Signals
Sander Koelstra,Christian Mühl,Mohammad Soleymani,Jong-Seok Lee,Ashkan Yazdani,Touradj Ebrahimi,Thierry Pun,Anton Nijholt,Ioannis Patras +8 more
TL;DR: A multimodal data set for the analysis of human affective states was presented and a novel method for stimuli selection is proposed using retrieval by affective tags from the last.fm website, video highlight detection, and an online assessment tool.
Journal ArticleDOI
Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden
Matthew D. Hellmann,Tudor-Eliade Ciuleanu,Adam Pluzanski,Jong-Seok Lee,Gregory A. Otterson,Clarisse Audigier-Valette,Elisa Minenza,Helena Linardou,Sjaak Burgers,Pamela Salman,Hossein Borghaei,Suresh S. Ramalingam,Julie R. Brahmer,Martin Reck,Kenneth J. O'Byrne,William J. Geese,George Green,Han Chang,Joseph D. Szustakowski,Prabhu Bhagavatheeswaran,Diane Healey,Yali Fu,F. E. Nathan,Luis Paz-Ares +23 more
TL;DR: The benefit of nivolumab plus ipilimumab over chemotherapy was broadly consistent within subgroups, including patients with a PD‐L1 expression level of at least 1% and those with a level of less than 1%.
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Predictive and Prognostic Impact of Epidermal Growth Factor Receptor Mutation in Non–Small-Cell Lung Cancer Patients Treated With Gefitinib
Sae-Won Han,Tae-You Kim,Pil Gyu Hwang,Soohyun Jeong,Jeongmi Kim,In Sil Choi,Do Youn Oh,Jee Hyun Kim,Dong Wan Kim,Doo Hyun Chung,Seock-Ah Im,Young Tae Kim,Jong-Seok Lee,Dae Seog Heo,Yung-Jue Bang,Noe Kyeong Kim +15 more
TL;DR: P-Akt overexpression was associated with prolonged TTP in patients with EGFR mutation, which further support the importance of EGFR mutations with regard to gefitinib sensitivity.
Journal ArticleDOI
Clonal History and Genetic Predictors of Transformation Into Small-Cell Carcinomas From Lung Adenocarcinomas.
June Koo Lee,Junehawk Lee,Sehui Kim,So Yeon Kim,Jeonghwan Youk,Seongyeol Park,Yohan An,Bhumsuk Keam,Dong Wan Kim,Dae Seog Heo,Young Tae Kim,Jin-Soo Kim,Sehyun Kim,Jong-Seok Lee,Se-Hoon Lee,Keunchil Park,Ja-Lok Ku,Yoon Kyung Jeon,Doo Hyun Chung,Peter J. Park,Joon Kim,Tae Min Kim,Young Seok Ju +22 more
TL;DR: EGFR TKI-resistant SCLCs are branched out early from the LADC clones that harbor completely inactivated RB1 and TP53, and they share a common clonal origin and undergoBranched evolutionary trajectories.