K
Katarzyna Młyniec
Researcher at Jagiellonian University Medical College
Publications - 48
Citations - 1729
Katarzyna Młyniec is an academic researcher from Jagiellonian University Medical College. The author has contributed to research in topics: Zinc deficiency & Antidepressant. The author has an hindex of 21, co-authored 41 publications receiving 1253 citations. Previous affiliations of Katarzyna Młyniec include Jagiellonian University & Polish Academy of Sciences.
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Antioxidant and anti-inflammatory effects of zinc. Zinc-dependent NF-κB signaling
TL;DR: In vitro studies have shown that zinc decreases NF-κB activation and its target genes, such as TNF-α and IL-1β, and increases the gene expression of A20 and PPAR-α, the two zinc finger proteins with anti-inflammatory properties.
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Essential elements in depression and anxiety. Part I
Katarzyna Młyniec,Magdalena Gaweł,Urszula Doboszewska,Urszula Doboszewska,Gabriela Starowicz,Karolina Pytka,Claire L. Davies,Bogusława Budziszewska,Bogusława Budziszewska +8 more
TL;DR: Copper, selenium, manganese, iodine and vanadium are focused on in the context of enzymes which require these elements as co-factors and are involved in the underlying pathophysiology of these disorders.
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GPR39 (Zinc Receptor) Knockout Mice Exhibit Depression-Like Behavior and CREB/BDNF Down-Regulation in the Hippocampus
TL;DR: The results of this study indicate the involvement of the GPR39 Zn2+-sensing receptor in the pathophysiology of depression with component of anxiety and does not support a role of G PR39 in hypothalamus-pituitary-adrenal axis regulation.
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Zinc deficiency induces behavioral alterations in the tail suspension test in mice. Effect of antidepressants.
TL;DR: The antidepressant-like effect of imipramine and escitalopram was significantly reduced in zinc-deprived mice, which suggests treatment-resistance induced by zinc deprivation, and indicates the developing response to zinc deficiency induced by a zinc-deficient diet.
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The involvement of the GPR39-Zn(2+)-sensing receptor in the pathophysiology of depression. Studies in rodent models and suicide victims.
Katarzyna Młyniec,Katarzyna Młyniec,Urszula Doboszewska,Bernadeta Szewczyk,Magdalena Sowa-Kućma,Paulina Misztak,Wojciech Piekoszewski,Franciszek Trela,Beata Ostachowicz,Gabriel Nowak +9 more
TL;DR: Down-regulation of CREB, BDNF, TrkB and GPR39 receptor found under zinc-deficient conditions in the hippocampus, may play an important role in the pathophysiology of mood disorders, since most of patients suffering from depression show lower serum zinc.