K
Keith Kerr
Researcher at University of Aberdeen
Publications - 11
Citations - 2255
Keith Kerr is an academic researcher from University of Aberdeen. The author has contributed to research in topics: Anaplastic lymphoma kinase & Tissue microarray. The author has an hindex of 6, co-authored 11 publications receiving 1695 citations. Previous affiliations of Keith Kerr include University of Birmingham & Seoul National University Bundang Hospital.
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Journal ArticleDOI
Tracking the Evolution of Non–Small-Cell Lung Cancer
Mariam Jamal-Hanjani,Gareth A. Wilson,Nicholas McGranahan,Nicolai Juul Birkbak,Thomas B.K. Watkins,Selvaraju Veeriah,Seema Shafi,Diana Johnson,Richard Mitter,Rachel Rosenthal,Max Salm,Stuart Horswell,Mickael Escudero,Nik Matthews,Andrew Rowan,Tim Chambers,David A. Moore,Samra Turajlic,Hang Xu,Siow Ming Lee,Martin Forster,Tanya Ahmad,Crispin T. Hiley,Christopher Abbosh,Mary Falzon,Elaine Borg,Teresa Marafioti,David Lawrence,Martin Hayward,Shyam Kolvekar,Nikolaos Panagiotopoulos,Sam M. Janes,Ricky Thakrar,Asia Ahmed,Fiona H Blackhall,Yvonne Summers,Rajesh Shah,Leena Dennis Joseph,Anne Marie Quinn,Phil Crosbie,Babu Naidu,Gary Middleton,Gerald Langman,Simon Trotter,Marianne Nicolson,Hardy Remmen,Keith Kerr,Mahendran Chetty,Lesley Gomersall,Dean A. Fennell,Apostolos Nakas,Sridhar Rathinam,Girija Anand,Sajid A. Khan,Peter Russell,Veni Ezhil,Babikir Ismail,Melanie Irvin-Sellers,Vineet Prakash,Jason F. Lester,Malgorzata Kornaszewska,Richard Attanoos,Haydn Adams,Helen Davies,Stefan C. Dentro,Philippe Taniere,Brendan O'Sullivan,Helen Lowe,John A. Hartley,Natasha Iles,Harriet Bell,Yenting Ngai,Jacqui Shaw,Javier Herrero,Zoltan Szallasi,Roland F. Schwarz,Aengus Stewart,Sergio A. Quezada,John Le Quesne,Peter Van Loo,Caroline Dive,Allan Hackshaw,Charles Swanton +82 more
TL;DR: Intratumor heterogeneity mediated through chromosome instability was associated with an increased risk of recurrence or death, a finding that supports the potential value of chromosome instability as a prognostic predictor.
Journal ArticleDOI
Programmed Death-Ligand 1 Immunohistochemistry Testing: A Review of Analytical Assays and Clinical Implementation in Non-Small-Cell Lung Cancer.
Reinhard Büttner,John R Gosney,Birgit Guldhammer Skov,Julien Adam,Noriko Motoi,Kenneth Joel Bloom,Manfred Dietel,John W. Longshore,Fernando Lopez-Rios,Frédérique Penault-Llorca,Giuseppe Viale,Andrew Wotherspoon,Keith Kerr,Ming-Sound Tsao +13 more
TL;DR: High concordance among 28-8, 22C3, and SP263 when assessing PD-L1 expression on tumor cell membranes suggests possible interchangeability of their clinical use for NSCLC but not for assessment ofPD-L 1 expression on immune cells.
Journal ArticleDOI
Prevalence and Clinical Outcomes for Patients With ALK-Positive Resected Stage I to III Adenocarcinoma: Results From the European Thoracic Oncology Platform Lungscape Project
Fiona H Blackhall,Solange Peters,Lukas Bubendorf,Urania Dafni,Keith Kerr,Henrik Hager,Alex Soltermann,Kenneth J. O'Byrne,Christophe Dooms,Aleksandra Sejda,Javier Hernández-Losa,Antonio Marchetti,Spasenija Savic,Qiang Tan,Erik Thunnissen,Ernst-Jan M. Speel,Richard T. Cheney,Daisuke Nonaka,Jeroen de Jong,Miguel Martorell,Igor Letovanec,Rafael Rosell,Rolf A. Stahel +22 more
TL;DR: Multivariable models, adjusted for patient, tumor, and treatment characteristics, and matched cohort analysis confirmed that ALK FISH positivity is a predictor for better overall survival (OS) and a screening strategy based on IHC or H-score could be envisaged.
Journal ArticleDOI
The role of the molecular footprint of EGFR in tailoring treatment decisions in NSCLC.
TL;DR: A review of the current methodologies used to identify such molecular markers can be found in this paper, where a number of techniques have been employed for genotypic assessment of tumour-associated DNA to identify EGFR mutations.
Prevalence and clinical outcomes for patients with ALK-positive resected stage I to III adenocarcinoma : results from the European Thoracic Oncology Platform Lungscape Project
Fiona H Blackhall,Solange Peters,Lukas Bubendorf,Urania Dafni,Keith Kerr,Henrik Hager,Alex Soltermann,Kenneth J. O'Byrne,Christophe Dooms,Aleksandra Sejda,Javier Hernández-Losa,Antonio Marchetti,Spasenija Savic,Qiang Tan,Erik Thunnissen,Ernst-Jan M. Speel,Richard T. Cheney,Daisuke Nonaka,Jeroen de Jong,Miguel Martorell,Igor Letovanec,Rafael Rosell,Rolf A. Stahel +22 more
TL;DR: The Lungscape ALK project was designed to address the prevalence and prognostic impact of ALK positivity in resected lung adenocarcinoma in a primarily European population as discussed by the authors.