K
Keith R. Jerome
Researcher at Fred Hutchinson Cancer Research Center
Publications - 340
Citations - 16831
Keith R. Jerome is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Medicine & Viral load. The author has an hindex of 56, co-authored 288 publications receiving 13158 citations. Previous affiliations of Keith R. Jerome include University of Washington & University of Düsseldorf.
Papers
More filters
Journal ArticleDOI
Covid-19 in Critically Ill Patients in the Seattle Region - Case Series.
Pavan K. Bhatraju,Bijan J Ghassemieh,Michelle Nichols,Richard Kim,Keith R. Jerome,Arun K. Nalla,Alexander L. Greninger,Sudhakar Pipavath,Mark M Wurfel,Laura Evans,Patricia M Kritek,T. Eoin West,Andrew M Luks,Anthony Gerbino,Christopher R. Dale,Jason D Goldman,D. Shane O’Mahony,Carmen Mikacenic +17 more
TL;DR: During the first 3 weeks of the Covid-19 outbreak in the Seattle area, the most common reasons for admission to the ICU were hypoxemic respiratory failure leading to mechanical ventilation, hypotension requiring vasopressor treatment, or both.
Journal ArticleDOI
Performance Characteristics of the Abbott Architect SARS-CoV-2 IgG Assay and Seroprevalence in Boise, Idaho.
Andrew Bryan,Gregory Pepper,Mark H. Wener,Susan L. Fink,Chihiro Morishima,Anu Chaudhary,Keith R. Jerome,Keith R. Jerome,Patrick C. Mathias,Alexander L. Greninger,Alexander L. Greninger +10 more
TL;DR: It is expected that the availability of high-quality serological testing will be a key tool in the fight against SARS-CoV-2 as the limited circulation of the virus in the western United States.
Journal ArticleDOI
Neutralizing Antibodies Correlate with Protection from SARS-CoV-2 in Humans during a Fishery Vessel Outbreak with a High Attack Rate.
Amin Addetia,Katharine H.D. Crawford,Katharine H.D. Crawford,Adam S. Dingens,Haiying Zhu,Pavitra Roychoudhury,Pavitra Roychoudhury,Meei Li Huang,Meei Li Huang,Keith R. Jerome,Keith R. Jerome,Jesse D. Bloom,Jesse D. Bloom,Jesse D. Bloom,Alexander L. Greninger,Alexander L. Greninger +15 more
TL;DR: The development of vaccines against SARS-CoV-2 would be greatly facilitated by the identification of immunological correlates of protection in humans, as the presence of neutralizing antibodies from prior infection was significantly associated with protection against reinfection.
Journal ArticleDOI
Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing.
Julia Joung,Alim Ladha,Makoto Saito,Nam-Gyun Kim,Ann E. Woolley,Michael Segel,Robert P.J. Barretto,Amardeep Ranu,Rhiannon K. Macrae,Guilhem Faure,Eleonora I. Ioannidi,Rohan N. Krajeski,Robert Bruneau,Meei Li W. Huang,Xu G. Yu,Jonathan Z. Li,Bruce D. Walker,Deborah T. Hung,Alexander L. Greninger,Keith R. Jerome,Jonathan S. Gootenberg,Omar O. Abudayyeh,Feng Zhang +22 more
TL;DR: A new method for the detection of SARS-CoV-2 combines simplified extraction of RNA with isothermal amplification and CRISPR (clustered regularly int…) with a CRISpr-Based Test.
Journal ArticleDOI
Comparative Performance of SARS-CoV-2 Detection Assays Using Seven Different Primer-Probe Sets and One Assay Kit.
Arun K. Nalla,Amanda M. Casto,Amanda M. Casto,Meei Li W. Huang,Garrett A. Perchetti,Reigran Sampoleo,Lasata Shrestha,Yulun Wei,Haiying Zhu,Keith R. Jerome,Keith R. Jerome,Alexander L. Greninger +11 more
TL;DR: All assays tested were found to be highly specific for SARS-CoV-2, with no cross-reactivity with other respiratory viruses observed in the authors' analyses regardless of the primer-probe set or kit used.