K
Kenji Kabashima
Researcher at Kyoto University
Publications - 798
Citations - 24358
Kenji Kabashima is an academic researcher from Kyoto University. The author has contributed to research in topics: Medicine & Atopic dermatitis. The author has an hindex of 70, co-authored 686 publications receiving 18708 citations. Previous affiliations of Kenji Kabashima include Singapore Immunology Network & University of Occupational and Environmental Health Japan.
Papers
More filters
Journal ArticleDOI
Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations.
TL;DR: The mechanisms of action and the limitations of anti-PD-1/PD-L1 and anti-CTLA-4 antibodies which are the two types of checkpoint inhibitors currently available to patients are examined and the future avenues of their use in melanoma and other cancers are explored.
Journal ArticleDOI
Prostaglandin D2 as a Mediator of Allergic Asthma
Toshiyuki Matsuoka,Masakazu Hirata,Hiroyuki Tanaka,Yoshimasa Takahashi,Takahiko Murata,Kenji Kabashima,Yukihiko Sugimoto,Takuya Kobayashi,Fumitaka Ushikubi,Yoshiya Aze,Naomi Eguchi,Yoshihiro Urade,Nobuaki Yoshida,Kazushi Kimura,Akira Mizoguchi,Yoshihito Honda,Hiroichi Nagai,Shuh Narumiya +17 more
TL;DR: In this article, the role of prostaglandin D2 (PGD2) in allergic asthma was investigated by the generation of mice deficient in the PGD receptor (DP).
Journal ArticleDOI
Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma†
Ryosuke Hino,Kenji Kabashima,Kenji Kabashima,Yu Kato,Hiroaki Yagi,Motonobu Nakamura,Tasuku Honjo,Taku Okazaki,Taku Okazaki,Yoshiki Tokura +9 more
TL;DR: Investigation of the mechanism underlining the immunosuppression of melanoma patients focused on programmed cell death‐1/PD‐1 ligand 1 (PD‐L1) interaction between tumor cells and T cells.
Journal ArticleDOI
Possible pathogenic role of Th17 cells for atopic dermatitis.
TL;DR: In this paper, the involvement of T helper cell 17 (Th17) in atopic dermatitis (AD) is investigated, and the percentage of Th17 cells was increased in peripheral blood of AD patients and associated with severity of AD.
Journal ArticleDOI
Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches
Svetoslav Chakarov,Hwee Ying Lim,Leonard Tan,Sheau Yng Lim,Peter See,Josephine Lum,Xiao Meng Zhang,Shihui Foo,Satoshi Nakamizo,Kaibo Duan,Wan Ting Kong,Rebecca Gentek,Akhila Balachander,Daniel Carbajo,Camille Bleriot,Benoit Malleret,Benoit Malleret,John Kit Chung Tam,Sonia Baig,Muhammad Shabeer,Sue-Anne Ee Shiow Toh,Andreas Schlitzer,Anis Larbi,Thomas Marichal,Bernard Malissen,Jinmiao Chen,Michael Poidinger,Kenji Kabashima,Kenji Kabashima,Marc Bajénoff,Lai Guan Ng,Veronique Angeli,Florent Ginhoux +32 more
TL;DR: In this article, two independent resident tissue macrophages (RTMs) populations are identified across tissues with specific niche-dependent phenotype and functional programming, and they are slowly replaced by Ly6Chi monocytes.