L
L. Luciani
Researcher at Boehringer Ingelheim
Publications - 14
Citations - 99
L. Luciani is an academic researcher from Boehringer Ingelheim. The author has contributed to research in topics: Cost effectiveness & Internal medicine. The author has an hindex of 5, co-authored 11 publications receiving 69 citations.
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Journal ArticleDOI
Cost-Effectiveness Analysis of Afatinib versus Gefitinib for First-Line Treatment of Advanced EGFR-Mutated Advanced Non–Small Cell Lung Cancers
Christos Chouaid,L. Luciani,Katell LeLay,Pascal Do,Jaafar Bennouna,Maurice Pérol,Denis Moro-Sibilot,Alain Vergnenegre,Gérard de Pouvourville +8 more
TL;DR: First‐line afatinib appears cost‐effective compared with gefitinib for patients with EGFR mutation–positive NSCLCs, and Deterministic and probabilistic sensitivity analyses were conducted.
Journal ArticleDOI
Identification of Patient Profiles with High Risk of Hospital Re-Admissions for Acute COPD Exacerbations (AECOPD) in France Using a Machine Learning Model
Arnaud Cavailles,Boris Melloni,Stéphane Motola,Florent Dayde,Marie Laurent,Katell Le Lay,D. Caumette,L. Luciani,Pierre Louis Lleu,Geoffrey Berthon,Thomas Flament +10 more
TL;DR: Since hospitalisation for an acute exacerbation is the most important determinant of future rehospitalisations, management of COPD needs to focus on interventions aimed at decreasing the rehospitalisation risk of in order to lower the burden of disease.
Journal ArticleDOI
Patient preference for chronic obstructive pulmonary disease (COPD) treatment inhalers: a discrete choice experiment in France.
Christos Chouaid,N. Germain,Gérard de Pouvourville,Samuel Aballéa,D Korchagina,Michael Baldwin,Katell Le Lay,L. Luciani,Mondher Toumi,Philippe Devillier +9 more
TL;DR: The strongest drivers of preference in French users of inhalation devices for COPD are shape, dose counter and reusability, which are important to patients and should be taken into account by clinicians prescribing these devices.
Journal ArticleDOI
Evaluating the cost-effectiveness of afatinib after platinum-based therapy for the treatment of squamous non-small-cell lung cancer in France.
Maud Pignata,Christos Chouaid,Katell Le Lay,L. Luciani,Ceilidh McConnachie,J. Gordon,Stéphane Roze +6 more
TL;DR: Based on data from the LUX-Lung 8 trial, afatinib was projected to improve clinical outcomes versus erlotinib, with a 97% probability of being cost-effective assuming a willingness to pay of EUR70,000 per QALY gained, after platinum-based therapy in patients with squamous NSCLC in France.
Journal ArticleDOI
Health economic evaluation in idiopathic pulmonary fibrosis in France.
TL;DR: It is found that nintedanib appears to be a more cost-effective therapeutic option than pirfenidone in a French setting, due to fewer acute exacerbations and a better tolerability profile.