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L

L. Luciani

Researcher at Boehringer Ingelheim

Publications -  14
Citations -  99

L. Luciani is an academic researcher from Boehringer Ingelheim. The author has contributed to research in topics: Cost effectiveness & Internal medicine. The author has an hindex of 5, co-authored 11 publications receiving 69 citations.

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Cost-Effectiveness Analysis of Afatinib versus Gefitinib for First-Line Treatment of Advanced EGFR-Mutated Advanced Non–Small Cell Lung Cancers

TL;DR: First‐line afatinib appears cost‐effective compared with gefitinib for patients with EGFR mutation–positive NSCLCs, and Deterministic and probabilistic sensitivity analyses were conducted.
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Identification of Patient Profiles with High Risk of Hospital Re-Admissions for Acute COPD Exacerbations (AECOPD) in France Using a Machine Learning Model

TL;DR: Since hospitalisation for an acute exacerbation is the most important determinant of future rehospitalisations, management of COPD needs to focus on interventions aimed at decreasing the rehospitalisation risk of in order to lower the burden of disease.
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Patient preference for chronic obstructive pulmonary disease (COPD) treatment inhalers: a discrete choice experiment in France.

TL;DR: The strongest drivers of preference in French users of inhalation devices for COPD are shape, dose counter and reusability, which are important to patients and should be taken into account by clinicians prescribing these devices.
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Evaluating the cost-effectiveness of afatinib after platinum-based therapy for the treatment of squamous non-small-cell lung cancer in France.

TL;DR: Based on data from the LUX-Lung 8 trial, afatinib was projected to improve clinical outcomes versus erlotinib, with a 97% probability of being cost-effective assuming a willingness to pay of EUR70,000 per QALY gained, after platinum-based therapy in patients with squamous NSCLC in France.
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Health economic evaluation in idiopathic pulmonary fibrosis in France.

TL;DR: It is found that nintedanib appears to be a more cost-effective therapeutic option than pirfenidone in a French setting, due to fewer acute exacerbations and a better tolerability profile.