A methodical gross examination should be undertaken in all births and the results incorporated in the patient’s record.

The Pathology of the Human Placenta

On the regulation and control of fibrinolysis. Edward Kowalski Memorial Lecture.

The Uterine Spiral Arteries In Human Pregnancy: Facts and Controversies

Assessment of menstrual blood loss using a pictorial chart

ACOG practice bulletin: Clinical management guidelines for obstetrician-gynecologists

The previous literature on menstrual blood loss studies was reviewed. A new study was conducted to ascertain the variation of menstrual blood loss at various ages and to establish the upper normal limit of menstrual blood loss. The study involved 476 women of all ages in Goteborg Sweden. Amenorrheic women were excluded from the study. Measurement of hemoglobin concentration plasma iron concentration and hematocrit levels indicated wide variation among women. No statistically significant differences in menstrual blood loss were observed among age groups except that women 50 and older had the highest and women 15 and under the lowest mean loss levels. It was concluded that a loss of 60-80 ml is normal; losses above 80 ml should be considered pathological.

Menstrual blood loss--a population study. Variation at different ages and attempts to define normality.

Menstrual blood loss???a population study. variation at different ages and attempts to define normality

Treatment of menorrhagia.

Menstrual blood loss and iron deficiency.

Treatment of menorrhagia with an antifibrinolytic agent tranexamic acid (AMCA) was investigated by double-blind trial and dose-response studies. 36 women aged 15-49 years were included in the study. The decrease in blood loss during AMCA treatment was statistically significant (.05 < p < .1). No difference was seen between the women with and those without fibroids. 17 of the women reported no side effects. 2 women had side effects only with the placebo and 6 did so on both regimens. In 7 women side effects occurred only with the high dosage. The main side effects were diarrhea and abdominal pains.

Lennart Nilsson

Papers

Menstrual blood loss--a population study. Variation at different ages and attempts to define normality.

Menstrual blood loss???a population study. variation at different ages and attempts to define normality

Treatment of menorrhagia.

Menstrual blood loss and iron deficiency.

Treatment Of Menorrhagia With An Antifibrinolytic Agent, Tranexamic Acid (Amca): A Double Blind Investigation