L
Leslie R. Rowe
Researcher at ARUP Laboratories
Publications - 36
Citations - 881
Leslie R. Rowe is an academic researcher from ARUP Laboratories. The author has contributed to research in topics: Chromosomal inversion & Fine-needle aspiration. The author has an hindex of 13, co-authored 32 publications receiving 811 citations. Previous affiliations of Leslie R. Rowe include University of Utah.
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Journal ArticleDOI
PAM50 Breast Cancer Subtyping by RT-qPCR and Concordance with Standard Clinical Molecular Markers
Roy R. L. Bastien,Álvaro Rodríguez-Lescure,Mark T. W. Ebbert,Aleix Prat,Aleix Prat,Blanca Munárriz,Leslie R. Rowe,Patricia Miller,Manuel Ruiz-Borrego,Daniel Anderson,Bradley W. Lyons,Isabel Alvarez,Tracy Dowell,David Wall,Miguel Ángel Seguí,Lee Barley,Kenneth M. Boucher,Emilio Alba,Lisa Pappas,Carole Davis,Ignacio Aranda,Christiane Fauron,Inge J. Stijleman,José Palacios,Antonio Antón,Eva Carrasco,Rosalía Caballero,Matthew J. Ellis,Torsten O. Nielsen,Charles M. Perou,Mark E. Astill,Philip S. Bernard,Philip S. Bernard,Miguel Martin +33 more
TL;DR: The standard immunohistochemical panel for breast cancer (ER, PR, and HER2) does not adequately identify the PAM50 gene expression subtypes and single gene scoring for ESR1, PGR, and ERBB2 was more prognostic than the corresponding IHC markers as shown in a multivariate analysis.
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Utility of BRAF V600E mutation detection in cytologically indeterminate thyroid nodules
TL;DR: When used with indeterminate FNA samples, BRAF mutation analysis may be a useful adjunct technique for confirming the diagnosis of malignancy in an otherwise equivocal case, however, overall tumor cell content of some archival FNA smear slides is a limiting factor for mutation detection.
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U-type exchange is the most frequent mechanism for inverted duplication with terminal deletion rearrangements
Leslie R. Rowe,Ji-Yun Lee,Lyndsey Rector,Erin B. Kaminsky,Arthur R. Brothman,Christa Lese Martin,Sarah T. South +6 more
TL;DR: 17 new cases of inverted duplication with terminal deletion are described, demonstrating that U-type exchange is the most frequent mechanism for this rearrangement and can be observed on most, or perhaps all, chromosome arms.
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The unsatisfactory ThinPrep Pap Test: missed opportunity for disease detection?
TL;DR: In this paper, the potential benefits of reprocessing unsatisfactory ThinPrep Pap Tests (Cytyc, Boxborough, MA) were analyzed. But the results were limited to the case of cervical cytology specimens.
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Detection of BRAF V600E activating mutation in papillary thyroid carcinoma using PCR with allele-specific fluorescent probe melting curve analysis.
TL;DR: Identification of the BRAF V600E activating mutation in routine FFPE pathology samples by a rapid laboratory method such as LCPCR could have significant value in management and treatment of papillary thyroid carcinoma.