L
Li Zhang
Researcher at Sun Yat-sen University
Publications - 774
Citations - 33980
Li Zhang is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 67, co-authored 667 publications receiving 25692 citations. Previous affiliations of Li Zhang include Wuhan University & Wuhan Jinyintan Hospital.
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Journal ArticleDOI
Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China
Chaomin Wu,Xiaoyan Chen,Yanping Cai,Jia’an Xia,Xing Zhou,Sha Xu,Han-Ping Huang,Li Zhang,Xia Zhou,Chunling Du,Yuye Zhang,Juan Song,Sijiao Wang,Yencheng Chao,Zeyong Yang,Jie Xu,Xin Zhou,Dechang Chen,Weining Xiong,Lei Xu,Feng Zhou,Jinjun Jiang,Chunxue Bai,Zheng Junhua,Yuanlin Song +24 more
TL;DR: Although high fever was associated with the development of ARDS, it was also associated with better outcomes among patients with ARDS and treatment with methylprednisolone may be beneficial for patients who develop ARDS.
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Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study
Caicun Zhou,Yi-Long Wu,Gongyan Chen,Jifeng Feng,Xiaoqing Liu,Changli Wang,Shucai Zhang,Jie Wang,Songwen Zhou,Shengxiang Ren,Shun Lu,Li Zhang,Chengping Hu,Chunhong Hu,Yi Luo,Lei Chen,Ming Ye,Jian'An Huang,Xiuyi Zhi,Yiping Zhang,Qingyu Xiu,Jun Ma,Changxuan You +22 more
TL;DR: It is suggested that erlotinib is important for first-line treatment of patients with advanced EGFR mutation-positive NSCLC, and was associated with more favourable tolerability than standard chemotherapy.
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Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
Chun-Xiao Song,Keith E. Szulwach,Ye Fu,Qing Dai,Chengqi Yi,Xuekun Li,Yujing Li,Chih Hsin Chen,Wen Zhang,Xing Jian,Jing Wang,Li Zhang,Timothy J. Looney,Baichen Zhang,Lucy A. Godley,Leslie M. Hicks,Bruce T. Lahn,Peng Jin,Chuan He +18 more
TL;DR: This method uses the T4 bacteriophage β-glucosyltransferase to transfer an engineered glucose moiety containing an azide group onto the hydroxyl group of 5-hmC, a recently identified epigenetic modification present in substantial amounts in certain mammalian cell types.
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Afatinib versus gefitinib as first-line treatment of patients with EGFR mutation-positive non-small-cell lung cancer (LUX-Lung 7): a phase 2B, open-label, randomised controlled trial
Keunchil Park,Eng Huat Tan,Kenneth J. O'Byrne,Li Zhang,Michael Boyer,Tony Mok,Vera Hirsh,James Chih-Hsin Yang,Ki Hyeong Lee,Shun Lu,Yuankai Shi,Sang We Kim,Janessa Laskin,Dong Wan Kim,Catherine Dubos Arvis,Karl Kölbeck,Scott A. Laurie,Chun-Ming Tsai,Mehdi Shahidi,MI-Young Kim,Dan Massey,V. Zazulina,Luis Paz-Ares +22 more
TL;DR: Afatinib significantly improved outcomes in treatment-naive patients with EGFR-mutated NSCLC compared with gefitinib, with a manageable tolerability profile.
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Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysis
Pierre Blanchard,Pierre Blanchard,Anne W.M. Lee,Sophie Marguet,Julie Leclercq,Wai Tong Ng,Jun Ma,Anthony T.C. Chan,Pei Yu Huang,Ellen Benhamou,Ellen Benhamou,Guopei Zhu,Daniel T.T. Chua,Yong Chen,Hai-Qiang Mai,Dora L.W. Kwong,Shie Lee Cheah,James J. Moon,Yuk Tung,Kwan-Hwa Chi,George Fountzilas,Li Zhang,Edwin P. Hui,Taixiang Lu,Jean Bourhis,Jean Pierre Pignon,Jean Pierre Pignon +26 more
TL;DR: The results confirm that the addition of concomitant chemotherapy to radiotherapy significantly improves survival in patients with locoregionally advanced nasopharyngeal carcinoma.