Luca Brazzi

TL;DR: It is hypothesize that the different COVID-19 patterns found at presentation in the emergency department depend on the interaction between three factors: the severity of the infection, the host response, physiological reserve and comorbidities; the ventilatory responsiveness of the patient to hypoxemia; and the time elapsed between the onset of the disease and the observation in the hospital.

TL;DR: Whether increasing the cardiac index to a supranormal level (cardiac-index group) or increasing mixed venous oxygen saturation to a normal level (oxygen-saturation group) would decrease morbidity and mortality among critically ill patients, as compared with a control group in which the target was a normal cardiac index.

TL;DR: Although placing patients with acute respiratory failure in a prone position improves their oxygenation, it does not improve survival.

TL;DR: One third of patients presented with mild ALI, but more than half rapidly evolved to acute respiratory distress syndrome (ARDS), confirming the grading of severity between the two forms of the syndrome.

TL;DR: A combination of topical and systemic prophylactic antibiotics reduces RTIs and overall mortality in adult patients receiving intensive care and the risk of resistance occurring as a negative consequence of antibiotic use was appropriately explored.