M
Marc-Thorsten Hütt
Researcher at Jacobs University Bremen
Publications - 151
Citations - 2525
Marc-Thorsten Hütt is an academic researcher from Jacobs University Bremen. The author has contributed to research in topics: Network topology & Systems biology. The author has an hindex of 27, co-authored 140 publications receiving 2087 citations. Previous affiliations of Marc-Thorsten Hütt include International University, Cambodia & Technische Universität Darmstadt.
Papers
More filters
Journal ArticleDOI
Organization of excitable dynamics in hierarchical biological networks.
TL;DR: The results demonstrate that two principal topological aspects of hierarchical networks, node centrality and network modularity, correlate with the network activity patterns at different levels of spontaneous network activation.
Journal ArticleDOI
Connectivity and complex systems: learning from a multi-disciplinary perspective
Laura Turnbull,Marc-Thorsten Hütt,Andreas A. Ioannides,Stuart Kininmonth,Ronald E. Poeppl,Klement Tockner,Klement Tockner,Louise J. Bracken,Saskia Keesstra,Lichan Liu,Rens Masselink,Anthony J. Parsons +11 more
TL;DR: This review evaluates how a connectivity-based approach has generated new understanding of structural-functional relationships that characterise complex systems and proposes a ‘common toolbox’ underpinned by network-based approaches that can advance connectivity studies by overcoming existing constraints.
Journal ArticleDOI
Dissecting the logical types of network control in gene expression profiles
TL;DR: This work looks at the properties of effective networks derived from significant gene expression changes under variation of the two forms of control and finds that upon limitations of one type of control the other type can compensate for compromised regulation.
Journal ArticleDOI
Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease
Robert Häsler,Raheleh Sheibani-Tezerji,Anupam Sinha,Matthias Barann,Ateequr Rehman,Daniela Esser,Konrad Aden,Carolin Knecht,B. Brandt,Susanna Nikolaus,Sascha Schäuble,Christoph Kaleta,Andre Franke,Christoph Fretter,Werner Müller,Marc-Thorsten Hütt,Michael Krawczak,Stefan Schreiber,Philip Rosenstiel +18 more
TL;DR: The authors' results provide strong evidence that the interplay between microbiome and host transcriptome is drastically perturbed in Crohn's disease and UC, and integrating multiple OMICs levels appears to be a promising approach to further disentangle the complexity of IBD.
Journal ArticleDOI
Analog regulation of metabolic demand
TL;DR: The results show that DNA supercoiling coordinates gene expression with metabolism, and it is shown that this control is acting directly because the potential role of the TRN as a mediator is excluded.