Marie Paule Schneider

TL;DR: It is suggested that objective monitoring of compliance using electronic devices may be a useful step in the management of patients with refractory hypertension, as it enables physicians to take rational decisions based on reliable and objective data of drug compliance and hence to improve blood pressure control.

TL;DR: A multitude of indirect measures of adherence exist in the literature, however, there is no “gold” standard for measuring adherence to medications and future research and practice interventions should use an internationally accepted, operational standardized definition of medication adherence.

TL;DR: A fairly high prevalence of swallowing difficulties in polypharmacy patients attending their community pharmacies is reported, with intentional non adherence and altering the oral dose formulation were the most common and potentially harmful strategies used by patients to overcome their swallowing difficulties.

TL;DR: Self-report of two or more missed doses of ART is associated with an increased risk of both viral failure and death, and a simple adherence question helps identify patients at risk for negative clinical outcomes and offers opportunities for intervention.

TL;DR: Overall, practicability and acceptability of the IDAS II and the MEMS device were similar and could be a useful tool for the management of long-term therapies.