Martin Downes

TL;DR: The AXIS tool was developed in a way that it can be used across disciplines to aid the inclusion of CSSs in systematic reviews, guidelines and clinical decision-making in a number of different disciplines.

TL;DR: A novel role for the AR–KDM complex in bladder cancer initiation and progression is supported, JMJD2A is identified as a promising prognostic biomarker, and targeting of the KDM activity as an effective potential approach for bladder cancer growth inhibition is demonstrated.

TL;DR: In this article, the effects of pharmacological inhibition of LSD1 on the proliferation of these bladder cancer cells was determined, and the results support a novel role for the AR-KDM complex in bladder cancer initiation and progression, identify JMJD2A as a promising prognostic biomarker, and demonstrate targeting of the KDM activity as an effective potential approach for bladder cancer growth inhibition.

TL;DR: There is a lack of high level evidence for telephone consultations in a GP setting; however, current evidence suggests that telephone consultations as an alternative to face-to-face general practice consultations offers an appropriate option in certain settings.

TL;DR: The results suggest that alterations in the expression of VEGF and VEGFR2 receptors are associated with disease stage and recurrence.