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Max Bylesjö
Researcher at Umeå University
Publications - 34
Citations - 3811
Max Bylesjö is an academic researcher from Umeå University. The author has contributed to research in topics: DNA damage & Cancer. The author has an hindex of 22, co-authored 34 publications receiving 3382 citations.
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Journal ArticleDOI
OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification†
Max Bylesjö,Mattias Rantalainen,Olivier Cloarec,Jeremy K. Nicholson,Elaine Holmes,Johan Trygg +5 more
TL;DR: In this paper, class-orthogonal variation can be exploited to augment classificaiton analysis (OPLS-DA) for the purpose of discriminant analysis, and the OPLS method can be used to augment classification.
Journal ArticleDOI
The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models
Leming Shi,Gregory Campbell,Wendell D. Jones,Fabien Campagne,Zhining Wen,Stephen J. Walker,Zhenqiang Su,Tzu Ming Chu,Federico Goodsaid,Lajos Pusztai,John D. Shaughnessy,André Oberthuer,Russell S. Thomas,Richard S. Paules,Mark R. Fielden,Bart Barlogie,Weijie Chen,Pan Du,Matthias Fischer,Cesare Furlanello,Brandon D. Gallas,Xijin Ge,Dalila B. Megherbi,W. Fraser Symmans,May D. Wang,John Zhang,Hans Bitter,Benedikt Brors,Pierre R. Bushel,Max Bylesjö,Minjun Chen,Jie Cheng,Jing Cheng,Jeff W. Chou,Timothy Davison,Mauro Delorenzi,Youping Deng,Viswanath Devanarayan,David J. Dix,Joaquín Dopazo,Kevin C. Dorff,Fathi Elloumi,Jianqing Fan,Shicai Fan,Xiaohui Fan,Hong Fang,Nina Gonzaludo,Kenneth R. Hess,Huixiao Hong,Jun Huan,Rafael A. Irizarry,Richard S. Judson,Dilafruz Juraeva,Samir Lababidi,Christophe G. Lambert,Li Li,Yanen Li,Zhen Li,Simon Lin,Guozhen Liu,Edward K. Lobenhofer,J. Luo,Wen Luo,Matthew N. McCall,Yuri Nikolsky,Gene Pennello,Roger Perkins,Reena Philip,Vlad Popovici,Nathan D. Price,Feng Qian,Andreas Scherer,Tieliu Shi,Weiwei Shi,Jaeyun Sung,Danielle Thierry-Mieg,Jean Thierry-Mieg,Venkata Thodima,Johan Trygg,Lakshmi Vishnuvajjala,Sue Jane Wang,Jianping Wu,Yichao Wu,Qian Xie,Waleed A. Yousef,Liang Zhang,Xuegong Zhang,Sheng Zhong,Yiming Zhou,Sheng Zhu,Dhivya Arasappan,Wenjun Bao,Anne Bergstrom Lucas,Frank Berthold,Richard J. Brennan,Andreas Buness,Jennifer G. Catalano,Chang Chang,Rong Chen,Yiyu Cheng,Jian Cui,Wendy Czika,Francesca Demichelis,Xutao Deng,Damir Dosymbekov,Roland Eils,Yang Feng,Jennifer Fostel,Stephanie Fulmer-Smentek,James C. Fuscoe,Laurent Gatto,Weigong Ge,Darlene R. Goldstein,Li Guo,Donald N. Halbert,Jing Han,Stephen C. Harris,Christos Hatzis,Damir Herman,Jianping Huang,Roderick V. Jensen,Rui Jiang,Charles D. Johnson,Giuseppe Jurman,Yvonne Kahlert,Sadik A. Khuder,Matthias Kohl,Jianying Li,Li Lee,Menglong Li,Quan Zhen Li,Shao Li,Zhiguang Li,Jie Liu,Ying Liu,Zhichao Liu,Lu Meng,Manuel Madera,Francisco Martinez-Murillo,Ignacio Medina,Joseph Meehan,K. Miclaus,Richard A. Moffitt,David Montaner,Piali Mukherjee,George Mulligan,Padraic Neville,Tatiana Nikolskaya,Baitang Ning,Grier P. Page,Joel S. Parker,R. Mitchell Parry,Xuejun Peng,Ron L. Peterson,John H. Phan,Brian Quanz,Yi Ren,Samantha Riccadonna,Alan H. Roter,Frank W. Samuelson,Martin Schumacher,Joseph D. Shambaugh,Qiang Shi,Richard Shippy,Shengzhu Si,Aaron Smalter,Christos Sotiriou,Mat Soukup,Frank Staedtler,Guido Steiner,Todd H. Stokes,Qinglan Sun,Pei Yi Tan,Rong Tang,Zivana Tezak,Brett T. Thorn,Marina Tsyganova,Yaron Turpaz,S. Vega,Roberto Visintainer,Juergen Von Frese,Charles Wang,Eric Wang,Junwei Wang,Wei Wang,Frank Westermann,James C. Willey,Matthew Woods,Shujian Wu,Nianqing Xiao,Joshua Xu,Lei Xu,Lun Yang,Xiao Zeng,Jialu Zhang,Li Zheng,Min Zhang,Chen Zhao,Raj K. Puri,Uwe Scherf,Weida Tong,Russell D. Wolfinger +201 more
TL;DR: P predictive models for classifying a sample with respect to one of 13 endpoints indicative of lung or liver toxicity in rodents, or of breast cancer, multiple myeloma or neuroblastoma in humans are generated.
Journal ArticleDOI
LAMINA: a tool for rapid quantification of leaf size and shape parameters
Max Bylesjö,Vincent Segura,Raju Y. Soolanayakanahally,Anne M. Rae,Johan Trygg,Petter Gustafsson,Stefan Jansson,Nathaniel R. Street +7 more
TL;DR: LAMINA (Leaf shApe deterMINAtion), a new tool for the automated analysis of images of leaves, is developed and it is shown that the software provides an efficient and accurate means of analysing leaf area in large datasets in an automated or semi-automated work flow.
Journal ArticleDOI
Data integration in plant biology: the O2PLS method for combined modeling of transcript and metabolite data.
TL;DR: This study demonstrates that the O2PLS multivariate regression method can be used for combining 'omics' types of data and shows how the models can be validated and interpreted to identify biologically relevant events.
Journal ArticleDOI
Development and Independent Validation of a Prognostic Assay for Stage II Colon Cancer Using Formalin-Fixed Paraffin-Embedded Tissue
Richard D. Kennedy,Max Bylesjö,Peter Kerr,Timothy Davison,Julie Black,Elaine W. Kay,Robert J Holt,Vitali Proutski,Miika Ahdesmaki,V. M. Farztdinov,Nicolas Goffard,Peter Hey,F. A. McDyer,Karl Mulligan,Julie Mussen,Eamonn J. O'Brien,Gavin R. Oliver,Steven Walker,Jude M. Mulligan,Claire Wilson,Andreas Winter,Diarmuid O'Donoghue,Hugh Mulcahy,Jacintha O'Sullivan,Kieran Sheahan,John Hyland,Rajiv Dhir,Oliver F. Bathe,Ola Winqvist,Upender Manne,Chandrakumar Shanmugam,Sridhar Ramaswamy,Eduardo J. Leon,William I. Smith,Ultan McDermott,Richard H. Wilson,Daniel B. Longley,John L. Marshall,Robert Cummins,Daniel J. Sargent,Patrick G. Johnston,D. Paul Harkin +41 more
TL;DR: This gene signature represents a novel prognostic biomarker for patients with stage II colon cancer that can be applied to FFPE tumor samples that was shown to perform independently from known prognostic factors.