M
Michael Dray
Researcher at Waikato Hospital
Publications - 23
Citations - 391
Michael Dray is an academic researcher from Waikato Hospital. The author has contributed to research in topics: Germline mutation & Rotator cuff injury. The author has an hindex of 11, co-authored 23 publications receiving 305 citations.
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Journal ArticleDOI
Interactions between tenocytes and monosodium urate monohydrate crystals: implications for tendon involvement in gout
Ashika Chhana,Karen E. Callon,Michael Dray,Bregina Pool,Dorit Naot,Greg D. Gamble,Brendan Coleman,Geraldine M. McCarthy,Fiona M McQueen,Jillian Cornish,Nicola Dalbeth +10 more
TL;DR: Data indicate that monosodium urate monohydrate crystals directly interact with tenocytes to reduce cell viability and function, which may contribute to tendon damage in people with advanced gout.
Journal ArticleDOI
Reversible Deterioration in Hypophosphatasia Caused by Renal Failure With Bisphosphonate Treatment
Tim Cundy,Toshimi Michigami,Kanako Tachikawa,Michael Dray,John F. Collins,Eleftherios P. Paschalis,Sonja Gamsjaeger,Andreas Roschger,Nadja Fratzl-Zelman,Paul Roschger,Klaus Klaushofer +10 more
TL;DR: This case illustrates how pharmacological (bisphosphonate treatment) and physiologic changes in the “environment” can dramatically affect the phenotype of a genetic disorder.
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The Effects of Monosodium Urate Monohydrate Crystals on Chondrocyte Viability and Function: Implications for Development of Cartilage Damage in Gout
Ashika Chhana,K. E. Callon,Bregina Pool,Dorit Naot,Gregory D. Gamble,Michael Dray,Rocco P. Pitto,Jarome Bentley,Fiona M McQueen,Jillian Cornish,Nicola Dalbeth +10 more
TL;DR: Investigation of the effects of monosodium urate monohydrate (MSU) crystals on chondrocyte viability and function found they contribute to cartilage damage in gout through reduction of chondromic viability and promotion of a catabolic state.
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Local application of lactoferrin promotes bone regeneration in a rat critical-sized calvarial defect model as demonstrated by micro-CT and histological analysis.
Ryan Gao,Maureen Watson,Karen E. Callon,Donna Tuari,Michael Dray,Dorit Naot,Satya Amirapu,Jacob T. Munro,Jillian Cornish,David S. Musson +9 more
TL;DR: It is demonstrated that local application of lactoferrin significantly increased bone regeneration in a rat critical‐sized calvarial defect model and has therapeutic potential to improve the poor clinical outcomes associated with bony non‐union.
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Augmentation with an ovine forestomach matrix scaffold improves histological outcomes of rotator cuff repair in a rat model
Matthew Street,Ashvin Thambyah,Michael Dray,Satya Amirapu,Donna Tuari,Karen E. Callon,Julie D. McIntosh,Kristina Burkert,P. Rod Dunbar,Brendan Coleman,Jillian Cornish,David S. Musson +11 more
TL;DR: Improved histological healing is shown with OFM augmentation in augmenting rotator cuff repair, indicating that ECM scaffolds offer a promising solution to a difficult clinical problem.