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Nevins W. Todd
Researcher at University of Maryland, Baltimore
Publications - 70
Citations - 4427
Nevins W. Todd is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Lung cancer & Idiopathic pulmonary fibrosis. The author has an hindex of 27, co-authored 64 publications receiving 3882 citations. Previous affiliations of Nevins W. Todd include Veterans Health Administration.
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Journal ArticleDOI
Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer.
Feng Jiang,Qi Qiu,Abha Khanna,Nevins W. Todd,Janaki Deepak,Lingxiao Xing,Huijun Wang,Zhenqiu Liu,Yun Su,Sanford A. Stass,Ruth L. Katz +10 more
TL;DR: Immunohistochemical analysis of 303 clinical specimens from three independent cohorts of lung cancer patients and controls show that expression of ALDH1 is positively correlated with the stage and grade of lung tumors and related to a poor prognosis for the patients with early-stage lung cancer.
Journal ArticleDOI
Plasma microRNAs as potential biomarkers for non-small-cell lung cancer
Jun Shen,Nevins W. Todd,Howard Zhang,Lei Yu,Xing Lingxiao,Xing Lingxiao,Yuping Mei,Maria A. Guarnera,Jipei Liao,Amy Chou,Changwan Larry Lu,Zhengran Jiang,Hong-Bin Fang,Ruth L. Katz,Feng Jiang +14 more
TL;DR: Altered expressions of the miRNAs in plasma would provide potential blood-based biomarkers for NSCLC.
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Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers
Lei Yu,Nevins W. Todd,Lingxiao Xing,Ying Xie,Howard Zhang,Zhenqiu Liu,Hong-Bin Fang,Jian Zhang,Ruth L. Katz,Feng Jiang +9 more
TL;DR: A panel of miRNAs that can be used as highly sensitive and specific sputum markers for early detection of lung adenocarcinoma were developed and demonstrated the potential of translation to laboratory settings for improving the early detection.
Journal ArticleDOI
Molecular and cellular mechanisms of pulmonary fibrosis.
Nevins W. Todd,Nevins W. Todd,Irina G. Luzina,Irina G. Luzina,Sergei P. Atamas,Sergei P. Atamas +5 more
TL;DR: Three broad areas which have been explored that may be responsible for the combination of altered lung fibroblasts, loss of alveolar epithelial cells, and excessive accumulation of ECM are discussed: inflammation and immune mechanisms, oxidative stress and oxidative signaling, and procoagulant mechanisms.
Journal ArticleDOI
Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer.
Ying Xie,Nevins W. Todd,Zhenqiu Liu,Min Zhan,Hong-Bin Fang,Hong Peng,Mohammed Alattar,Janaki Deepak,Sanford A. Stass,Feng Jiang +9 more
TL;DR: The measurement of altered miRNA expression in sputum could be a useful noninvasive approach for the diagnosis of lung cancer.